Epidemiology of Restless Legs Syndrome in Korean Adults

Cho, Yong Won; Shin, Won Chul; Yun, Chang Ho; Hong, Seung Bong; Kim, Ju Han; Allen, Richard P.; Earley, Christopher J.

doi:10.1093/sleep/31.2.219

Cited by 122 publications

(93 citation statements)

References 21 publications

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“…Three previous reports (2 Korean, 1 Chinese) showed an exceptionally high RLS prevalence (7.2-8.3%) despite using a differential diagnostic approach [20,21,47]. Cho et al [20] used the Johns Hopkins telephone diagnostic interview.…”

Section: Discussionmentioning

confidence: 99%

“…Cho et al [20] used the Johns Hopkins telephone diagnostic interview. Although they used a stratified and multistage random sample, the telephone survey response rate was only 11.8%, raising the possibility that only those subjects who were specifically interested in sleep problems participated in the study (ascertainment bias).…”

Section: Discussionmentioning

confidence: 99%

“…The reported prevalence of RLS ranges from 3 to 25% in Europe [9], and the prevalence is generally low (< 2%) in Asian countries including Singapore, Taiwan, China, and Japan [12][13][14][15][16][17][18]. However, in most epidemiologic studies on Korean adults, the RLS prevalence is relatively high (4.5-12.1%) [19][20][21][22][23][24][25]. The discrepancy in the RLS prevalence between Korea and other Asian countries may be partly explained by differences in the diagnostic criteria and survey methods that are adopted for each study.…”

Section: Prevalence and Characteristics Of Restless Legsmentioning

confidence: 99%

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Prevalence and Characteristics of Restless Legs Syndrome in Korean Adults: A Study in Two Independent Samples of the General Population

Kim¹,

Yoon²,

Park³

et al. 2019

Neuroepidemiology

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Background: Restless legs syndrome (RLS) is a common sleep disorder, although it has a low prevalence in Asian populations. However, the reported RLS prevalence in Korean adults is mostly 4.5–12.1%, which is higher than that reported in other Asian populations. This study aimed to diagnose RLS and exclude mimicking conditions in 2 independent samples of Korean adults, and to compare its prevalence to that from previous studies performed in Asian countries. Methods: Study populations included a (1) nationwide stratified random sample (n = 2,824; age 19–79 years) and (2) community-based cohort (n = 2,685; age 47–79 years). We applied the Cambridge-Hopkins diagnostic questionnaire to diagnose RLS and differentiate it from RLS mimics. Sleep-related symptoms, mood, and medical conditions were compared between the RLS and non-RLS groups. Prior studies of the RLS prevalence in Asia were systematically reviewed and compared to our findings. Results: The adjusted RLS prevalence was 0.4 and 1.3% in populations 1 and 2, respectively. In both populations, subjects with RLS had more depression. The prevalence of RLS mimics was 5.1 and 2.6%, in populations 1 and 2, respectively. The RLS prevalence in Asia was higher when RLS was defined by the presence of essential clinical features and lower when a differential diagnosis was additionally implemented. Conclusions: The RLS prevalence in Korean adults considering RLS mimics is comparable to that in adults from other Asian countries (< 2%). The reported RLS prevalence varies depending on the diagnostic method employed.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Prevalence and Characteristics Of Restless Legsmentioning

confidence: 99%

See 1 more Smart Citation

Prevalence and Characteristics of Restless Legs Syndrome in Korean Adults: A Study in Two Independent Samples of the General Population

Kim¹,

Yoon²,

Park³

et al. 2019

Neuroepidemiology

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“…It has been recurrently observed a decrease in the prevalence of RLS in individuals older than 60/70 years of age 17,18,22 . Men with RLS, compared to individuals without RLS, have higher mortality independent to other known risk factors such as cancer, cardiovascular disease and hypertension 23 .…”

Section: Epidemiologymentioning

confidence: 98%

“…The prevalence of RLS is between 5%-10% 17,18,19,20 . In a study conducted in a Brazilian city, RLS prevalence was estimated at 6.4% 8 .…”

Section: Epidemiologymentioning

confidence: 99%

Brazilian consensus on guidelines for diagnosis and treatment for restless legs syndrome

Fröhlich

Éckeli

Bacelar³

et al. 2015

Arq. Neuro-Psiquiatr.

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Restless Legs Syndrome and Akathisia in Parkinson's Disease

Iranzo

Comella

2011

Parkinson's Disease

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Epidemiology of Restless Legs Syndrome in Korean Adults

Abstract: RLS is common and underdiagnosed in Korea with nearly 1% of the population reporting disturbed sleep related to their RLS. These results are comparable to other countries.

Cited by 122 publications

References 21 publications

Prevalence and Characteristics of Restless Legs Syndrome in Korean Adults: A Study in Two Independent Samples of the General Population

Prevalence and Characteristics of Restless Legs Syndrome in Korean Adults: A Study in Two Independent Samples of the General Population

Brazilian consensus on guidelines for diagnosis and treatment for restless legs syndrome

Restless Legs Syndrome and Akathisia in Parkinson's Disease

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