Epidemiology of Helicobacter Pylori in Dialysis Patients

Review of Helicobacter pylori Infection and Chronic Renal Failure

“…Previously, eight studies showed significantly lower prevalence of H. pylori infection in patients receiving hemodialysis (8/36 studies, 22.2%) (20,21,25,36,38,48,53,57) compared with controls and one study has found a significantly lower prevalence of H. pylori infection in patients receiving CAPD (1/5 studies, 20.0%) (21); whereas only one study reported that Iranian hemodialysis patients (63.0%) and chronic renal failure patients (66.2%) had significantly higher prevalence of H. pylori infection compared with normal individuals (27.5%) (Table 1) (9). However, since the prevalence of H. pylori infection in the Iranian population is reported to be more than 60% in other reports (63,64), further studies are required to clarify this discrepancy in the Iranian population.…”

“…The gastric mucosa of approximately 50% of the world's population is infected with H. pylori, and the infection levels exceed 70% in some developing areas (14,15). Helicobacter pylori infection plays a crucial role in the development of gastrointestinal diseases, such as peptic ulcer, gastric hyperplastic polyps, gastric adenoma, gastric cancer, and gastric mucosa associated-lymphoid tissue lymphoma, both in individuals with normal renal function and in chronic renal failure patients receiving hemodialysis and CAPD (Tables 1 and 2) (4-9, 16,[18][19][20][21][22][23][24][25][26][27][28][29][30][31][32]34,[36][37][38][39][40][41][42][43][44][45][47][48][49][50][51][52][53][54][55][56][57][58][59][60].…”

“…[4][5][6][7][8][9]16,[18][19][20][21][22][23][24][25][26][27][28][29][30][31][32]34,[36][37][38][39][40][41][42][43][44][45][48][49][50][51][52][53][54][55][56][57][58][59][60], the prevalence of H. pylori infection in patients receiving chronic hemodialysis and CAPD are 43.9% ([95% CI: 42.2-45.6%], 1 435/3 272) and 34.8% ([29.6-40.2%], 113/325), respectively, which is significantly lower than in individuals with normal renal function both with and without gastrointestinal symptoms (49.8% [48.0-51.7%], 1476/2961, P < 0.001).There is variation in H. pylori infection rates among different countries. It may, therefore, be better to evaluate the infection rate in various countries.…”

Helicobacter Pylori Infection in Patients with End-Stage Renal Disease

“…A significant relationship between anti-H. pylori antibody prevalence and dyspepsia in dialysis patients (13) and renal transplant recipients (13,17) has been reported in some but not all series (12,18,20,25,26,76). In the general population, approximately 50% of patients with symptomatic non-ulcer dyspepsia are infected with H. pylori (44).…”

“…There is limited information on H. pylori in dialysis patients and renal transplant recipients (7-28). Many studies have been based on serologic assays (8, 11,13,14,18,20,25,28) and have yielded conflicting prevalence rates. The clinical significance of the presence of H. pylori in ESRD remains unclear.…”