Epidemiology and clinical profile of individuals with cleft lip and palate utilising specialised academic treatment centres in South Africa

Hlongwa, P.; Rispel, Laetitia C.

doi:10.1371/journal.pone.0215931

Cited by 38 publications

(62 citation statements)

References 50 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…6 In relation to sex, there was an association between CLP and males, and between CP and females; this corroborates recent studies on the epidemiological profile of clefts in South Africa and China. 33,34 These results were also similar to those for the Brazilian surveys conducted in the states of Alagoas, Ceará, Mato Grosso, Minas Gerais, Paraná, Recife, São Paulo and Sergipe. 12,19,20,22,23,27,29 One likely explanation for the association of CP with females is that the secondary palate of the male human embryo is more advanced in the fusion process than that of the female during the critical periods of palate formation.…”

Section: Discussionsupporting

confidence: 85%

Prevalence of cleft lip and palate and associated factors in Brazil's Midwest: a single-center study

Errari-Piloni

Barros

Jesuino³

et al. 2021

Braz. oral res.

View full text Add to dashboard Cite

Section: Discussionsupporting

confidence: 85%

Prevalence of cleft lip and palate and associated factors in Brazil's Midwest: a single-center study

Errari-Piloni

Barros

Jesuino³

et al. 2021

Braz. oral res.

View full text Add to dashboard Cite

“…The overall prevalence was 3.11 per 1,000 live births indicating a higher figure compared to those obtained in Caucasian populations (approximately 1 per 1000 births) and Asian populations (approximately 1.7 per 1000 births) [10,13]. Nigerian literature reviewed revealed that the prevalence of cleft anomalies was approximately 0.37/1,000 live births, a Ugandan study reported 1.45/1, 000 live births, Tunisia, 1.40/1,000 live births and South Africa, 0.3/1000 live births [14][15][16][17]. In an earlier study conducted at Addis Ababa Ethio-Swedish children's hospital, 8% of children under study were treated for cleft deformities [18] and prevalence of CLP was approximately 1.49/1,000 live births [5].…”

Section: Discussionmentioning

confidence: 99%

Anatomical patterns of cleft lip and palate deformities among neonates in Mekelle, Tigray, Ethiopia; implication of environmental impact

2019

View full text Add to dashboard Cite

Background Cleft lip and palate deformities are considered one of the most common birth defects of the head and neck that pose significant medical, psychosocial and financial burdens on the affected individuals and families, especially in low income communities. The etiology and pathogenesis of cleft lip and palate is complex and is known to involve genetic and/or environmental factors. Objective To assess the patterns of anatomical cleft lip and palate deformities among neonates in Mekelle and Ayder Comprehensive Specialized hospitals, Tigray, Northern Ethiopia. Methods A hospital-based retrospective study was conducted from May 2017 to June 2017 at Mekelle and Ayder Comprehensive Specialized hospitals, both in Mekelle city. Data was collected from all medical charts of neonates registered from 2011 to 2016 and analyzed using SPSS version 21.0 and OpenEpi software. Results were presented using tables and graphs; Chi-square test was used to look for an association between variables, odds ratio to determine the strength of association of selected variables using multinomial logistic regression model, while Fisher Exact (Clopper-Pearson) was used to compare yearly prevalence. Results Of 37,152 neonatal charts analyzed, 119 (0.32%) cases were identified as having cleft deformities. 38.7, 17.6, and 43.7% of this figure had cleft lips, cleft palates and both cleft lip and palate respectively. 46 (38.7%) neonates had lateral patterns of cleft lip deformities with 56.5% located unilaterally on the right and 43.5% unilaterally on the left. Of 52 (43.7%) neonates with cleft lip and palate deformities, 40.4% were located bilaterally while 38.5 and 21.2% were located unilaterally on the left and right, respectively. Associated malformations were: cardiac (3.4%), central nervous system (1.7%) and limb deformities (5.9%). The overall prevalence of cleft deformities was found to be 3.11 per 1000 live births. Conclusion The study showed a higher prevalence of cleft deformities than that reported in Addis Ababa and some other African countries. A higher occurrence of left unilateral pattern of cleft lip and palate was observed whereas a higher right unilateral pattern of cleft lip was identified. The higher prevalence of cleft lip and palate recorded in this region of Ethiopia may reflect an environmental impact.

show abstract

“…Cleft lip and palate is a significant congenital malformation in Kenya. Among African populations, Kenya reports 1.7/1000 live births, while Ethiopia reports 0.2/1000, Nigeria 0.5/1000, and Uganda 0.8/1000 (Hlongwa et al, 2019). Further, it is estimated that between 600 to 700 corrective surgeries are done in Kenya annually (Waweru, 2019).…”

Section: Cl/p In Kenyamentioning

confidence: 99%

Social stigma and cultural beliefs associated with cleft lip and/or palate: parental perceptions of their experience in Kenya

Kimotho

Macharia

2020

Humanit Soc Sci Commun

View full text Add to dashboard Cite

Cleft lip with or without cleft palate (CL/P)—a condition associated with speech, hearing, feeding, and dental problems, as well as anomalies of the bone and soft tissue around the mouth—is a common birth defect around the globe. The prevalence of this condition varies widely across different countries and regions, and is apparently highest among Asians and lowest among Africans. A review of literature reveals that there exists a dearth of information on experiences of parents of children with CL/P and stigma communication, as well as cultural beliefs associated with CL/P in Africa. To fill this gap, we conducted a descriptive qualitative study examining the experiences of parents of children with CL/P, stigma communication, and cultural beliefs associated with CL/P in Kenya. Twenty four in-depth interviews were done involving purposefully sampled parents of children born with CL/P at AIC CURE International Hospital in Nairobi, Kenya. Five overarching themes emerged under the lived experiences of parents of children with CL/P: Emotional experiences; relational experiences; burden of care and concerns; reaction by the public and friends; and source of social support. The stigma messages and beliefs associated with CL/P further exacerbated the stigma. The study revealed that stigma communication associated with CL/P remains a significant source of social and psychological anguish to parents and guardians of children with CL/P. These findings have critical implications for the management of stigma communication associated with CL/P. They point to the need for public awareness campaigns on CL/P to demystify the condition, its causes and treatment. The study shows that raising public awareness of CL/P would go a long way towards addressing the stigma associated with the condition. It underscores the need for open communication and engagement with all stakeholders to manage stigma communication associated with CL/P through culturally appropriate anti-stigma campaigns.

show abstract

Epidemiology and clinical profile of individuals with cleft lip and palate utilising specialised academic treatment centres in South Africa

Cited by 38 publications

References 50 publications

Prevalence of cleft lip and palate and associated factors in Brazil's Midwest: a single-center study

Prevalence of cleft lip and palate and associated factors in Brazil's Midwest: a single-center study

Anatomical patterns of cleft lip and palate deformities among neonates in Mekelle, Tigray, Ethiopia; implication of environmental impact

Social stigma and cultural beliefs associated with cleft lip and/or palate: parental perceptions of their experience in Kenya

Contact Info

Product

Resources

About