Epidemiologic evaluation of head and neck patients in a university hospital of Northwestern São Paulo State

Alvarenga, Larissa de Melo; Ruiz, Mariana Torreglosa; Pavarino, Érika Cristina; Ruback, Maurício José Cabral; Maníglia, José Victor; Goloni-Bertollo, Eny Maria

doi:10.1016/s1808-8694(15)30753-9

Cited by 23 publications

(1 citation statement)

References 20 publications

(22 reference statements)

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“…This study showed the effects of BIT for dysphagia in patients with HNC during RCT compared to speech therapy with a weekly frequency. The sample consisted of predominantly male individuals (55%), corroborating another author, however, the percentage of women was high [16]. A significant increase in female incidence is described in the literature, possibly due to changes in habits, increased tobacco and alcohol consumption, and other environmental exposures [17].…”

Section: Discussionsupporting

confidence: 67%

Effects of Brief and Intensive Therapy for Dysphagia in Patients with Head and Neck Cancer during Radio-Chemotherapy: A Pilot Study

Rossetto¹,

Gabriel²,

Simonetti³

et al. 2022

IJCST

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Objective: To verify the effectiveness of a Brief and Intensive Dysphagia Therapy programme, in patients with head and neck cancer, during radio-chemotherapy. Study Design: This is a randomized clinical trial - pilot project with a random sample consisting of 11 patients divided into two groups: 7 in the intervention group, who received brief and intensive therapy and 4 in the control group, with weekly therapy. The assessment instruments used were tongue pressure measurement, mouth-opening measures, oral intake scale and quality of life questionnaire. Patients were evaluated before radio-chemotherapy, after 15 days of speech therapy and after radio-chemotherapy. Results: The intervention group presented higher values of lingual apex pressure (p = 0.00), mouth opening maintenance from the second evaluation (35.14 ± 16.82 mm) until the end of the radio-chemotherapy (35.29 p± 5.93 mm), greater oral intake functionality (p = 0.00) and improvement in overall aspects of quality of life questionnaire (p = 0.05) after completion of brief and intensive therapy and radio-chemotherapy. Conclusion: Brief and intensive therapy presented superior results in the maintenance and/or rehabilitation of the swallowing mechanism in patients with head and neck cancer undergoing radio-chemotherapy.

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Section: Discussionsupporting

confidence: 67%

Effects of Brief and Intensive Therapy for Dysphagia in Patients with Head and Neck Cancer during Radio-Chemotherapy: A Pilot Study

Rossetto¹,

Gabriel²,

Simonetti³

et al. 2022

IJCST

View full text Add to dashboard Cite

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Familial Aggregation of Head and Neck Cancer in Taiwan

et al. 2020

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Objectives: Head and neck cancer (HNC) incidence has been increasing worldwide. We investigated the familial aggregation of developing HNC if a first-degree relative (FDR) is affected in a large database. Methods: This retrospective study utilized Taiwan National Health Insurance Database to assemble a cohort of all registered beneficiaries from 1997 to 2013 and identified diagnosed HNC patients with affected FDRs. Results: Of the 55,916 individuals diagnosed with HNC, 566 (1.01%) had affected FDRs. There were 525 (0.56%) males and 41 (0.05%) females. Age of onset of HNC was found to be earlier for those with an affected FDR at the fourth decade of life compared to the general population. The adjusted relative risks (RRs) of an individual with an affected FDR to develop HNC is 2.04 (95% confidence interval [CI], 1.85-2.26): 2.07 (95% CI, 1.88-2.29) if the affected relative was male, and 1.74 (95% CI, 1.31-2.30) if the affected relative was female. The greatest risk to develop HNC is if the affected individual is a twin with adjusted RR 33.04 (95% CI, 12.89-84.69). This is followed by an affected sibling at RR (95% CI) 3.46 (1.68-7.13), offspring at RR 2.28 (95% CI, 1.94-2.69), and parent at RR 1.66 (95% CI, 1.48-1.87). Conclusion: Familial tendency of HNC proves the probable contribution of genetic factors to develop cancer. In areca quid endemic region, there is a high likelihood that both environmental and genetic factors work in synergy to develop HNC.

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