Quality of Life in Head and Neck Cancer Patients

Sharma, Yash Pal; Mishra, Girish; Parikh, Vibhuti

doi:10.1007/s12070-019-01620-2

Cited by 27 publications

(35 citation statements)

References 21 publications

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“…For socioemotional component, activity, recreation and pain had minimum mean scores of 51.66, 56.61 and 56.67 respectively. In study by Judit Kadar-Nagy D. D. S (Hungary) 12 activity and recreation were reported as greatest issues among socioemotional domains post treatment. In contrast to our study, a study by Dzebo et al 9 reported mood and anxiety as biggest problem under this category.…”

Section: Discussionmentioning

confidence: 96%

Vocation and Mobility as Significant Modifiable Determinants For Quality Of Life Among Oral And Throat Cancer Patients - A Hospital Based Study From Southern India

Jain

Susila

Duraisamy

et al. 2023

Natl J Community Med

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Background: Quality of Life (QOL) is an important indicator of treatment outcome for cancer therapies. QOL researches help us to explore about the impairment caused by treatment and disease on one’s social life, day to day activities and psychological conditions. The objective is to assess the health related QOL in patients suffering from oral cavity and throat cancer and to find out factors associated with QOL. Methodology: Facility based cross sectional study design with consecutive sampling was used to achieve a sample size of 90 patients with oral cavity and throat cancer. Result: 71(78.88%) of study participants were independent and 19(21.11%) were partially dependent, none were completely dependent. Majority of the study population perceived a poor overall QOL as revelled by the findings that only 24.4% had best scoring in overall QOL domain. Weak Positive Correlation (R2=0.224) was seen between physical and socio- emotional component of QOL (p value <0.001). Education and cancer site were significantly associated with physical component while employment and Activity of Daily Living were associated with social component of QOL. Conclusion: There is a need to focus on ambulatory and vocational rehabilitation along with pain management for oral & throat CA patients as the study show an association of these factors with social component of QOL.

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Section: Discussionmentioning

confidence: 96%

Vocation and Mobility as Significant Modifiable Determinants For Quality Of Life Among Oral And Throat Cancer Patients - A Hospital Based Study From Southern India

Jain

Susila

Duraisamy

et al. 2023

Natl J Community Med

View full text Add to dashboard Cite

show abstract

“…The deficit was evident in the domains of delayed recall, letter fluency, psychomotor speed and executive function [ 33 ]. Furthermore, cognitive deficit was also associated with RT [ 19 ] and the extent or injury varies depending on the duration of RT completion [ 18 , 34 , 35 ] with the memory and executive function domains being the most affected [ 36 , 37 ]. In some studies, cognitive deficit was more pronounced in patients receiving 2 Gy fraction doses [ 38 – 40 ].…”

Section: Discussionmentioning

confidence: 99%

“…This suggests that patients might have good resilience by alleviating emotional distress and thus might not have a decrease in their QoL as they were better at coping with cancer [ 63 , 64 ]. The better resilience and acceptance could be due to the patients’ ages (52.76 ± 12.73 years), as previous studies had shown that patients aged more than 50 years showed a drop in physical domain rather than social domain [ 37 ] and emotional domain [ 65 , 66 ]. However, given that patients were taken from a government institution where only very minimal medical fees are required, thus, the financial burden was not a factor, contrary to studies suggesting financial difficulty is a factor in affecting QoL [ 64 , 67 ].…”

Section: Discussionmentioning

confidence: 99%

Remote assessment of cognition and quality of life following radiotherapy for nasopharyngeal carcinoma: deep-learning-based predictive models and MRI correlates

2023

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Purpose Irradiation of the brain regions from nasopharyngeal carcinoma (NPC) radiotherapy (RT) is frequently unavoidable, which may result in radiation-induced cognitive deficit. Using deep learning (DL), the study aims to develop prediction models in predicting compromised cognition in patients following NPC RT using remote assessments and determine their relation to the quality of life (QoL) and MRI changes. Methods Seventy patients (20–76 aged) with MRI imaging (pre- and post-RT (6 months–1 year)) and complete cognitive assessments were recruited. Hippocampus, temporal lobes (TLs), and cerebellum were delineated and dosimetry parameters were extracted. Assessments were given post-RT via telephone (Telephone Interview Cognitive Status (TICS), Telephone Montreal Cognitive Assessment (T-MoCA), Telephone Mini Addenbrooke’s Cognitive Examination (Tele-MACE), and QLQ-H&N 43). Regression and deep neural network (DNN) models were used to predict post-RT cognition using anatomical and treatment dose features. Results Remote cognitive assessments were inter-correlated ( r > 0.9). TLs showed significance in pre- and post-RT volume differences and cognitive deficits, that are correlated with RT-associated volume atrophy and dose distribution. Good classification accuracy based on DNN area under receiver operating curve (AUROC) for cognitive prediction (T-MoCA AUROC = 0.878, TICS AUROC = 0.89, Tele-MACE AUROC = 0.919). Conclusion DL-based prediction models assessed using remote assessments can assist in predicting cognitive deficit following NPC RT. Comparable results of remote assessments in assessing cognition suggest its possibility in replacing standard assessments. Implications for Cancer Survivors Application of prediction models in individual patient enables tailored interventions to be provided in managing cognitive changes following NPC RT. Supplementary information The online version contains supplementary material available at 10.1007/s11764-023-01371-8.

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“…Given the complexity of the disease and the sensitivity of the region, oral squamous cell carcinoma treatment should be multidisciplinary, with the highlight not only on the therapy but also on the supportive aftercare. The possible treatment approach involves surgery, radiotherapy, and chemotherapy, all of which severely reduce quality of life [ 7 , 8 ]. Even though the two latter therapeutical modalities are more conservative and preservative for the patient, in most cases, surgical excision is the best and main option [ 9 , 10 ].…”

Section: Introductionmentioning

confidence: 99%

Quality of Life and Aesthetic Satisfaction in Patients Who Underwent the “Commando Operation” with Pectoralis Major Myocutaneus Flap Reconstruction—A Case Series Study

et al. 2022

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The “commando operation” is an extensive surgical procedure used to treat patients with oral squamous carcinoma and metastasis in the cervical lymph nodes. While the procedure can be curative, it is also very mutilating, which consequently has a major impact on the patient’s quality of life. Several studies showed that the procedure is associated with loss of certain functions, such as impairments in speech, chewing, swallowing, and loss of taste and appetite. Furthermore, some of these impairments and their degree depend on the reconstruction method. However, the data regarding the functional impairments and aesthetic results in patients who underwent the “commando operation” along with the pectoralis major myocutaneus flap reconstruction are still inconclusive. This study included 34 patients that underwent partial glossectomy, ipsilateral modified radical neck dissection, pectoralis major myocutaneus flap reconstruction, and adjuvant radiotherapy. A structured questionnaire was used to evaluate aesthetical results and functional impairments as well as to grade the level of satisfaction with the functional and aesthetic outcomes both by the patients and by the operator. Most of the patients stated that their speech (N = 33; 97%) and salivation (N = 32; 94.2%) severely changed after the operation and that they cannot chew (N = 33; 97%) and swallow (N = 33; 97%) the same as before the operation. Moreover, almost half of the patients (N = 16; 47%) reported that they have severe sleep impairments. However, only few of the included patients stated that they sought professional help regarding the speech (N = 4; 11.7%), eating (N = 5; 14.7%), and sleeping (N = 4; 11.7%) disturbances. Additionally, there was a statistically significant difference between the operator and the patients in the subjective assessment of the aesthetic results (p = 0.047), as operators gave significantly better grades. Our results imply that this procedure and reconstructive method possibly cause impairments that have an impact on the patients’ wellbeing. Moreover, our outcomes also suggest that patients should be educated and rehabilitated after the “commando operation” since most of them were reluctant to seek professional help regarding their impairments. Lastly, sleep deficiency, which was observed after the procedure, should be further explored.

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Quality of Life in Head and Neck Cancer Patients

Cited by 27 publications

References 21 publications

Vocation and Mobility as Significant Modifiable Determinants For Quality Of Life Among Oral And Throat Cancer Patients - A Hospital Based Study From Southern India

Vocation and Mobility as Significant Modifiable Determinants For Quality Of Life Among Oral And Throat Cancer Patients - A Hospital Based Study From Southern India

Remote assessment of cognition and quality of life following radiotherapy for nasopharyngeal carcinoma: deep-learning-based predictive models and MRI correlates

Quality of Life and Aesthetic Satisfaction in Patients Who Underwent the “Commando Operation” with Pectoralis Major Myocutaneus Flap Reconstruction—A Case Series Study

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