Environmental fate of non-steroidal anti-inflammatory drugs in river water/sediment systems

Koumaki, Elena; Mamais, Daniel; Noutsopoulos, Constantinos

doi:10.1016/j.jhazmat.2016.03.026

Cited by 60 publications

(30 citation statements)

References 51 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In recent years, there is a growing consumption of nonsteroidal anti‐inflammatory drugs (NSAIDs). These drugs are used mainly as painkillers, in order to decrease fever and to prevent blood clots . The class of NSAIDs include lots of drugs like ibuprofen, diclofenac naproxen, and piroxicam (PIR).…”

Section: Introductionmentioning

confidence: 99%

“…The class of NSAIDs include lots of drugs like ibuprofen, diclofenac naproxen, and piroxicam (PIR). NSAIDs have been extensively detected in surface water and secondary effluents in concentrations ranging from ng L −1 –μg L −1 . The use of physical and chemical processes becomes an imperative for the treatment of such persistent pollutants, since conventional biological systems fail to effectively remove NSAIDs .…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Electrochemical Degradation of Piroxicam on a Boron‐Doped Diamond Anode: Investigation of Operating Parameters and Ultrasound Synergy

et al. 2018

View full text Add to dashboard Cite

The electrochemical oxidation of piroxicam (PIR), a representative nonsteroidal anti-inflammatory drug, was studied using boron-doped diamond (BDD) as anode. BDD exhibited superior efficiency in comparison with platinum electrodes in terms of PIR degradation. Removal of PIR follows pseudo-first-order kinetics and the apparent kinetic constants decreased from 0.138 to 0.0369 min À 1 as the initial PIR concentration increased from 245 to 975 μg L À 1 . Altering of the pH had little effect on electrolysis of PIR with slightly better removal at pH 9. The presence of 10 g L À 1 of tert-butanol inhibited PIR removal, indicating that its oxidation is caused by electro-generated hydroxyl radicals. Addition of 200 mg L À 1 sodium chloride increased the apparent kinetic constant more than ten times from 0.139 to 1.44 min À 1 . Similar behavior was observed in the case of bicarbonates and nitrates, possibly due to the generation of selective carbonate radicals and active oxygen species like nitric or nitrous oxides. Experiments were also conducted in various aqueous matrices and it was observed that the presence of humic acid delayed the degradation of PIR, while process efficiency was enhanced in bottled and surface water as well as in wastewater, due to the presence of inorganic ions. Coupling BDD electrolysis with ultrasound (at 14 W L À 1 , 20 kHz) increased the reaction rate of PIR destruction and the observed synergy was calculated at S = 44.6 %. order to keep temperature of the water below 35°C after 15 min of sonoelectrocatalysis. Liquid ChromatographyPIR was detected by modifying an HPLC method, described in our previous work. [48] The chromatographic system was a Waters Alliance 2695 connected with a Waters 2996 PDA detector. The column was a Kinetex XB-C18 100A column (2.6 μm, 2.1 mm × 150 mm and was connected with a 0.5 μm inline filter (KrudKatcher Ultra) (Phenomenex). The flow rate was 0.2 mL/min and the mobile phase consisted of 75 : 25 acetonitrile water. The column was thermostated to 45°C. The injection volume was 100 μL. After the separation, the concentration of PIR was measured using Waters 2996 Photo Diode Array detector at 350 nm.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Electrochemical Degradation of Piroxicam on a Boron‐Doped Diamond Anode: Investigation of Operating Parameters and Ultrasound Synergy

et al. 2018

View full text Add to dashboard Cite

show abstract

“…No obstante, por sus características físicas y químicas, Koumaki et al (2017) indican que en el agua superficial la eliminación de los MC está dada por procesos como hidrólisis, volatilización, adsorción, fotólisis y biodegradación. Dichos procesos pueden transformar los MC en cuestión de horas o días, incidiendo sobre su presencia.…”

Section: Presencia Y Concentración De Grupos Seleccionados (I IV De)unclassified

“…Condición que se confirmó en este estudio donde se encontró que tanto en la PTAR-C como en el agua superficial, la concentración del metabolito fue aproximadamente seis veces mayor que la de la carbamazepina. Koumaki et al (2017) consideran a la biodegradación como el principal mecanismo de eliminación del ibuprofeno en el agua superficial, con mayor eficiencia bajo condiciones aerobias, pues la tasa de eliminación disminuye cuando baja la concentración de oxígeno disuelto. Sin embargo, en el río Cauca esta biodegradación puede verse afectada debido a la continua descarga de este MC y a que la concentración de oxígeno disuelto ha llegado por debajo de 2 mg/L (Pérez et al 2012).…”

Section: Presencia Y Concentración De Grupos Seleccionados (I IV De)unclassified

“…De acuerdo con Koumaki et al (2017), el principal mecanismo de eliminación del naproxeno es la fotólisis, en menos de 24 horas. Sin embargo, se debe considerar que el río Cauca ha tenido eventos de alta turbiedad con valores máximos entre 476 y 1130 UNT (Montoya et al 2013), que interfieren con el paso de luz solar afectando dicha fotodegradación.…”

Section: Presencia Y Concentración De Grupos Seleccionados (I IV De)unclassified

See 1 more Smart Citation

Estudio Exploratorio De La Presencia De Microcontaminantes en El Ciclo Urbano Del Agua en Colombia: Caso De Estudio Santiago De Cali

Madera-Parra

Jiménez-Bambague

Toro-Vélez³

et al. 2018

Rev. Int. Contam. Ambie.

View full text Add to dashboard Cite

Palabras clave: compuestos farmacéuticos, disruptores endocrinos, agua potable, agua residual, agua superficial RESUMEN Los microcontaminantes incluyen una amplia gama de compuestos presentes en el ambiente en concentraciones de µg/L o ng/L. En este estudio se analizó la presencia y concentración de microcontaminantes como compuestos farmacéuticos y disruptores endocrinos en el ciclo urbano del agua de la ciudad de Santiago de Cali, Colombia, donde se incluyeron cuatro puntos de monitoreo de agua superficial, tres de agua potable y uno de agua residual. Se realizaron cinco jornadas de muestreo: un muestreo preliminar en el cual se cuantificaron 92 compuestos clasificados en cinco grupos de compuestos farmacéuticos (I, II, III, IV y V) y un grupo de disruptores endocrinos (DE), a partir del cual se priorizaron tres grupos a ser determinados en los cuatro muestreos siguientes. Los criterios de presencia, concentración, efectos sobre la biota acuática y financiamiento de la investigación, se emplearon para seleccionar los grupos I, IV y DE, los cuales tuvieron una presencia superior al 48 % y una concentración media de hasta 11 000 ng/L. Se encontró que los compuestos más relevantes, en términos de presencia y concentración en el ciclo urbano del agua fueron 10,11-dihydro-10,11-dihidroxicarbamazepina, ibuprofeno, naproxeno, gemfibrozilo, paracetamol, sulfametoxazol, estronas, 4-iso-nonilfenol y bisfenol A. La presencia en el ciclo urbano del agua de Cali genera una alerta por la potencial amenaza sobre los organismos acuáticos y la salud humana.Key words: pharmaceutical compounds, endocrine disruptors, drinking water, wastewater, superficial water ABSTRACT Micropollutants includes a wide variety of compounds in environmental concentrations of µg/L or ng/L. The presence and concentration of micropollutants, as pharmaceutical and endocrine disruptors compounds, were studied throughout the urban water cycle of Santiago de Cali city, Colombia. In order to do this, samples were collected in four points of surface water, three of drinking water and one of wastewater. Five samplings were carried out: one screening with 92 compounds measured, classified in five pharmaceutical compounds groups (I, II, III, IV and V) and one endocrine disruptors group Rev. Int.

show abstract

Emerging Contaminants: Analysis, Aquatic Compartments and Water Pollution

Morin‐Crini¹,

Lichtfouse²,

Liu³

et al. 2021

Emerging Contaminants Vol. 1

View full text Add to dashboard Cite

Over the past two decades, the presence of so-called emerging contaminants in various environmental compartments around the world, such as water, sediments, soils and atmosphere, and in a wide variety of consumer products has become a major concern for society, public health authorities, industry (namely food industry and water sector) and the agricultural sector. Some of these substances are endocrine disruptors and others are proven carcinogens and mutagens. In particular,

show abstract

Environmental fate of non-steroidal anti-inflammatory drugs in river water/sediment systems

Cited by 60 publications

References 51 publications

Electrochemical Degradation of Piroxicam on a Boron‐Doped Diamond Anode: Investigation of Operating Parameters and Ultrasound Synergy

Electrochemical Degradation of Piroxicam on a Boron‐Doped Diamond Anode: Investigation of Operating Parameters and Ultrasound Synergy

Estudio Exploratorio De La Presencia De Microcontaminantes en El Ciclo Urbano Del Agua en Colombia: Caso De Estudio Santiago De Cali

Emerging Contaminants: Analysis, Aquatic Compartments and Water Pollution

Contact Info

Product

Resources

About