Enhancing fluorescence signals from aluminium thin films and foils using polyelectrolyte multilayers

Enhancing the quality factor of grating coupled plasmon resonance in optical recording media

“…The polyelectrolytes were deposited in a layer-by-layer (LbL) fashion by alternately dipping the substrate in aqueous solutions of these polymers in concentration of 1 mg/ml. The LbL deposition is possible on any substrate such as metals, glass, plastic and even transparency sheets [10,11]. Thickness of one bilayer is approximately 3-4 nm [10,11].…”

“…The LbL deposition is possible on any substrate such as metals, glass, plastic and even transparency sheets [10,11]. Thickness of one bilayer is approximately 3-4 nm [10,11]. On the DVD grating substrates 2, 4, 6, 8, 10, 12, 14 and 16 bilayers (one cationic and one anionic polyelectrolyte together form one bilayer) were deposited.…”

“…Here we demonstrate an alternate method to enhance the Q factor of SPR from DVD substrates by depositing alternatively charged polymers in a layer-by-layer (LbL) manner on the grating surface prior to metallization. The LbL assembly is based on self-limiting electrostatic interactions of polyelectrolyte materials [10,11]. As the thickness of each layer is typically around 3 nm, the profile of the grating and consequently the plasmonic response can be precisely tuned.…”

Emerging technologies for biomedical analysis

“…Traditional biological recognition assays employing a static solid support continue to have widespread use both on commercial and experimental platforms. 1,3,7,[32][33][34][35][36] Their high sensitivity, versatility in detection methods, and adaptability for the quantication of a myriad of targets continue to make their replacement by other testing platforms a challenge (summary of techniques shown in Table 1). While these methods employ diverse tactics, a primary focus over the last several years has been to address a common pitfall of these assays: non-specic binding (NSB) and its limitation of the assays' potential sensitivity.…”

“…These include Whatman's FAST® slides, Oncyte-Avid slides, and Unisart slides. 6,[32][33][34][35][36] FAST® slides can be used to perform reverse phase protein arrays, traditional protein arrays and antibody arrays utilizing less sample than a traditional ELISA test. They also allow for the parallel quantitation of many samples to a limit of 1 pg mL À1 .…”