Enhanced organic−inorganic heterojunction of polypyrrole@Bi2WO6: Fabrication and application for sensitive photoelectrochemical immunoassay of creatine kinase-MB

Zhu, Li‐Bang; Lü, Lei; Wang, Haiyan; Fan, Gao-Chao; Chen, Yi-Ting; Zhang, Jia-Dong; Zhao, Weiwei

doi:10.1016/j.bios.2019.111349

Cited by 27 publications

(6 citation statements)

References 24 publications

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“…[6,14,15] Compared to the conventional inorganic semiconductor heterostructures, the emerging two-dimensional organic/inorganic hybrid van der Waals heterojunction offers the more perfect platform for the energy-band alignment engineering between the organic and inorganic semiconductors, and helps to realize more efficient heterostructure optoelectronic devices with new functionalities. [8,[16][17][18] The inorganic semiconductors usually have a larger carrier mobility yet higher growth temperatures, while the organics are generally characterized by greater flexibility and lower growth temperatures. [19][20][21][22] On the other hand, the conventional inorganic semiconductors usually rely on the high-energy vaporization processes, which usually involves continuous bombardment, clusters, and strong local heating in the contact region by high-energy atoms.…”

Section: Introductionmentioning

confidence: 99%

High-performance self-powered photodetector based on organic/inorganic hybrid van der Waals heterojunction of rubrene/silicon*

Zhou

Yin

et al. 2021

Chinese Phys. B

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Organic/inorganic hybrid van der Waals heterostructure with an atomically abrupt interface has attracted great research interests within the field of multifunctional electronic and optoelectronic devices. The integration of organic rubrene films with inorganic Si semiconductors can avoid the atomic mutual-diffusion at the interface, and provide the possibility of forming two-dimensional van der Waals heterojunction accompanied with the type-II energy band alignment, due to the transfer behaviors of majority carriers at the interface. In this study, the high-quality rubrene/Si van der Waals heterostructure with an electronically abrupt junction was prepared, and a self-powered photodetector was then constructed based on this hybrid heterojunction. The photodetector demonstrated an excellent switching response to the 1064 nm monochromatic light with large on/off current ratio of 7.0 × 103, the maximum photocurrent of 14.62 mA, the maximum responsivity of 2.07 A/W, the maximum detectivity of 2.9 × 1011 Jones, and a fast response time of 13.0 μs. This study offers important guidance for preparing high-quality rubrene/Si hybrid van der Waals heterostructure with desirable band alignment, and the designed heterojunction photodetector has an important application prospect in the field of multifunctional optoelectronics.

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Section: Introductionmentioning

confidence: 99%

High-performance self-powered photodetector based on organic/inorganic hybrid van der Waals heterojunction of rubrene/silicon*

Zhou

Yin

et al. 2021

Chinese Phys. B

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“…The intimate correlation between analyte concentration and variations in the photocurrent signal enables PEC sensors to achieve precise identification and quantitative analysis of targets. Thus far, great progress has been achieved in the development of nanostructured materials exhibiting outstanding PEC properties, encompassing organic semiconductor materials, , inorganic semiconductor materials, , and semiconductor-based heterojunctions. − Particularly, biocompatible nanomaterials with enhanced photoelectric conversion efficiency are frequently selected for modifying the electrode/solution interface in implantable PEC sensors . Combining the advantages of optical and electrochemical sensors, PEC sensors inherit attributes such as fast response, cost-effectiveness, and miniaturization .…”

Section: Sensing Strategies Of Implantable Chemical Sensorsmentioning

confidence: 99%

Recent Development of Implantable Chemical Sensors Utilizing Flexible and Biodegradable Materials for Biomedical Applications

Hu,

Wang,

Liu

et al. 2024

ACS Nano

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Implantable chemical sensors built with flexible and biodegradable materials exhibit immense potential for seamless integration with biological systems by matching the mechanical properties of soft tissues and eliminating device retraction procedures. Compared with conventional hospital-based blood tests, implantable chemical sensors have the capability to achieve real-time monitoring with high accuracy of important biomarkers such as metabolites, neurotransmitters, and proteins, offering valuable insights for clinical applications. These innovative sensors could provide essential information for preventive diagnosis and effective intervention. To date, despite extensive research on flexible and bioresorbable materials for implantable electronics, the development of chemical sensors has faced several challenges related to materials and device design, resulting in only a limited number of successful accomplishments. This review highlights recent advancements in implantable chemical sensors based on flexible and biodegradable materials, encompassing their sensing strategies, materials strategies, and geometric configurations. The following discussions focus on demonstrated detection of various objects including ions, small molecules, and a few examples of macromolecules using flexible and/or bioresorbable implantable chemical sensors. Finally, we will present current challenges and explore potential future directions.

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“…Creatine kinase detection with biosensors is being developed in the medical sector since this protein has been found to be a good biomarker for acute myocardial infarction (Ferreira et al., 2021). Detection is often based on antibody‐based recognition of the enzyme followed by electrochemical signal transduction on a nanomaterial‐modified electrode (Adhikari et al., 2019; Zhu et al., 2019). Substrate conversion‐based detection of CK was not identified.…”

Section: Tailored Biosensing Strategiesmentioning

confidence: 99%

Biomarkers and biosensors for the diagnosis of noncompliant pH, dark cutting beef predisposition, and welfare in cattle

Nelis

Bose

Broadbent

et al. 2022

Comp Rev Food Sci Food Safe

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Meat quality can be affected by stress, exhaustion, feed composition, and other physical and environmental conditions. These stressors can alter the pH in postmortem muscle, leading to high pH and low‐quality dark cutting (DC) beef, resulting in considerable economic loss. Moreover, the dark cutting prediction may equally provide a measure for animal welfare since it is directly related to animal stress. There are two needs to advance on‐site detection of dark cutters: (1) a clear indication that biomarker (signature compounds) levels in cattle correlate with stress and DC outcome; and (2) measuring these biomarkers rapidly and accurately on‐farm or the abattoir, depending on the objectives. This critical review assesses which small molecules and proteins have been identified as potential biomarkers of stress and dark cutting in cattle. We discuss the potential of promising small molecule biomarkers, including catecholamine/cortisol metabolites, lactate, succinate, inosine, glucose, and β‐hydroxybutyrate, and we identify a clear research gap for proteomic biomarker discovery in live cattle. We also explore the potential of chemical‐sensing and biosensing technologies, including direct electrochemical detection improved through nanotechnology (e.g., carbon and gold nanostructures), surface‐enhanced Raman spectroscopy in combination with chemometrics, and commercial hand‐held devices for small molecule detection. No current strategy exists to rapidly detect predictive meat quality biomarkers due to the need to further validate biomarkers and the fact that different biosensor types are needed to optimally detect different molecules. Nonetheless, several biomarker/biosensor combinations reported herein show excellent potential to enable the measurement of DC potential in live cattle.

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Enhanced organic−inorganic heterojunction of polypyrrole@Bi2WO6: Fabrication and application for sensitive photoelectrochemical immunoassay of creatine kinase-MB

Cited by 27 publications

References 24 publications

High-performance self-powered photodetector based on organic/inorganic hybrid van der Waals heterojunction of rubrene/silicon*

High-performance self-powered photodetector based on organic/inorganic hybrid van der Waals heterojunction of rubrene/silicon*

Recent Development of Implantable Chemical Sensors Utilizing Flexible and Biodegradable Materials for Biomedical Applications

Biomarkers and biosensors for the diagnosis of noncompliant pH, dark cutting beef predisposition, and welfare in cattle

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