Enhanced Extraction of Total Polyphenols Content from Mitragyna Speciosa (Korth.) Havil Leaves using the Natural Deep Eutectic Solvent-based Microwave-assisted Extraction Method

Ahmad, Islamudin; Prabowo, Wisnu Cahyo; Nur, Yuspian; Irawan, Lulu; Yusniah, Andi; Rahayu, Bakti P; Hidayati, Ramila; Nurlinda, Hesti; Herman,

doi:10.5220/0009564500720077

Cited by 2 publications

(3 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In line with the development of extraction technology with a high degree of selectivity, modern approaches are essential in developing more effective, selective, and high-yielding methods for target secondary metabolites [175]. In addition, a non-conventional green solvent-based extraction method has been developed, namely, the natural deep eutectic solvent-based microwave-assisted extraction method [176,177] and ultrasound-assisted extraction [178]. This method is very effective in attracting the target secondary metabolite compounds, mainly polyphenols and other non-alkaloid compounds.…”

Section: The Prospective Potential Of Mitragyna Species As a Pharmaceutical Productmentioning

confidence: 99%

“…This method is very effective in attracting the target secondary metabolite compounds, mainly polyphenols and other non-alkaloid compounds. The successful development of this modern extraction method has become one of the main keys to developing pharmaceutical products [176][177][178].…”

Section: The Prospective Potential Of Mitragyna Species As a Pharmaceutical Productmentioning

confidence: 99%

See 1 more Smart Citation

Mitragyna Species as Pharmacological Agents: From Abuse to Promising Pharmaceutical Products

Ahmad

Prabowo

Arifuddin

et al. 2022

Life

Self Cite

View full text Add to dashboard Cite

Mitragyna is a genus belonging to the Rubiaceae family and is a plant endemic to Asia and Africa. Traditionally, the plants of this genus were used by local people to treat some diseases from generation to generation. Mitragyna speciosa (Korth.) Havil. is a controversial plant from this genus, known under the trading name “kratom”, and contains more than 40 different types of alkaloids. Mitragynine and 7-hydroxymitragynine have agonist morphine-like effects on opioid receptors. Globally, Mitragyna plants have high economic value. However, regulations regarding the circulation and use of these commodities vary in several countries around the world. This review article aims to comprehensively examine Mitragyna plants (mainly M. speciosa) as potential pharmacological agents by looking at various aspects of the plants. A literature search was performed and information collected using electronic databases including Scopus, ScienceDirect, PubMed, directory open access journal (DOAJ), and Google Scholar in early 2020 to mid-2021. This narrative review highlights some aspects of this genus, including historical background and botanical origins, habitat, cultivation, its use in traditional medicine, phytochemistry, pharmacology and toxicity, abuse and addiction, legal issues, and the potential of Mitragyna species as pharmaceutical products.

show abstract

Section: The Prospective Potential Of Mitragyna Species As a Pharmaceutical Productmentioning

confidence: 99%

Section: The Prospective Potential Of Mitragyna Species As a Pharmaceutical Productmentioning

confidence: 99%

Mitragyna Species as Pharmacological Agents: From Abuse to Promising Pharmaceutical Products

Ahmad

Prabowo

Arifuddin

et al. 2022

Life

Self Cite

View full text Add to dashboard Cite

show abstract

“…The extraction was carried out for about 1 h at 80 ℃. Then the extract was filtered and evaporated to remove the solvent [6,7].…”

Section: Extraction Of Gedong Mango (Gl) and Mulberry Leaves (Ml) By ...mentioning

confidence: 99%

Nades Extract of Gedong Mango Leaves and Mulberry Leaves in Spray Gel as a Sunscreen

RIZKIYAN

Suharyani²,

Falya³

et al. 2022

Int J App Pharm

View full text Add to dashboard Cite

Objective: This study's purpose was to formulate a spray gel containing the combination extract of gedong mango leaves and mulberry leaves as a sunscreen preparation. Methods: Each leaf was extracted by Natural Deep Eutectic Solvent-Maceration Assisted Extraction (NADES-MAE) method. The extract (gedong mango and mulberry leaves) formulated in Carbopol Spray Gel/GM-CarSG) in a ratio of GL and ML were 3:0.5 (GM-CarSG 1); 3:3 (GM-CarSG 2); and 3:6 (GM-CarSG 3). Furthermore, the spray gel was evaluated, and the SPF value was determined. Results: The physical appearance, spreadability, pH, and viscosity of GM-CarSG 1, GM-CarSG 2, and GM-CarSG 3 meet the requirements. In addition, the three preparation have a sunscreen activity, with the SPF value of GM-CarSG 1, GM-CarSG 2, and GM-CarSG 3 being 2.08+0.03; 2.78+0.05; and 3.53+0.04, respectively. Conclusion: The results showed that the combination of GL and ML extract is potentially used as a sunscreen in spray gel preparation. The best formulation is GM-CarSG 3, which has the highest SPF value among them.

show abstract

Enhanced Extraction of Total Polyphenols Content from Mitragyna Speciosa (Korth.) Havil Leaves using the Natural Deep Eutectic Solvent-based Microwave-assisted Extraction Method

Cited by 2 publications

References 0 publications

Mitragyna Species as Pharmacological Agents: From Abuse to Promising Pharmaceutical Products

Mitragyna Species as Pharmacological Agents: From Abuse to Promising Pharmaceutical Products

Nades Extract of Gedong Mango Leaves and Mulberry Leaves in Spray Gel as a Sunscreen

Contact Info

Product

Resources

About