Endothelin-1 Levels in Severe Burn Injuries

Onuoha, Gracey N.; Alpar, E. K.; Gowar, John P

doi:10.1001/archsurg.135.12.1418

Cited by 3 publications

(1 citation statement)

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“…However, for completeness sake, other possibilities include the possible trigger by emotional stress from the burn injury and admission to the hospital or caused by pathophysiologic response to the burn injury, including: (i) leukocytosis and thrombocytosis with possible activation of platelets and increasing of formation of platelet‐leukocyte complexes. In fact, antiplatelet therapy is a proposed treatment option for secondary RP in adults with scleroderma (4); (ii) Increased blood levels of certain cytokines including tumor necrosis factor alpha and/or Endothelin‐1 known to be elevated in some patients with burn injury (5,6) that have been described as possibly contributing to the development of RP (7).…”

Section: Discussionmentioning

confidence: 99%

Raynaud’s phenomenon in a child presenting as oxygen desaturation during transfusion with cold blood

Zhang

Coté

2008

Pediatric Anesthesia

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We report a case of Raynaud's phenomenon (RP) triggered by transfusion of cold blood to a pediatric burn patient under general anesthesia. The child was febrile so a decision was made to not use a blood warmer. When the blood was rapidly administered the child suddenly developed 'desaturation'. The child was placed on 100% oxygen, adequate ventilation assured, and the color of his oral mucosa assessed as 'pink'. Placement of the oximeter on the opposite hand revealed 100% saturation. To our knowledge, this is the first case of apparent RP reported in a pediatric patient triggered by transfusion of cold blood.

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Section: Discussionmentioning

confidence: 99%