Raynaud’s phenomenon in a child presenting as oxygen desaturation during transfusion with cold blood

Zhang, Xiaopeng; Coté, Charles J.

doi:10.1111/j.1460-9592.2008.02782.x

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Assess Risk Factors and Comorbidities1

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“…The pathogenesis was related to direct virus‐induced endothelial damage leading to the activation of platelets and subsequent vasoconstrictive response. Zhang and Cotè reported typical RP triggered by the transfusion of cold blood in a 2‐year‐old burn patient under general anesthesia.…”

Section: Assess Risk Factors and Comorbiditiesmentioning

confidence: 99%

Handy Hints About Raynaud's Phenomenon in Children: A Critical Review

Rigante

Fastiggi

Ricci

et al. 2017

Pediatric Dermatology

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Raynaud's phenomenon (RP) is a vasospastic disorder characterized by recurrent self-limited episodes of skin pallor, cyanosis, and hyperemia caused by paroxysmal spasms in the small arteries of the fingers and toes and can occur in any age group. Hands, feet, nose, ears, and nipples can be affected. The diagnosis is made clinically, assessing varying degrees of ischemia in the involved areas of skin, but this transient ischemia may also herald the onset of connective tissue disease. Investigation is recommended when RP starts in childhood to exclude an underlying autoimmune condition and close follow-up for its development. Management of RP in children includes conservative and pharmacologic treatments.

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Section: Assess Risk Factors and Comorbiditiesmentioning

confidence: 99%