Endophthalmitis Rate in Immediately Sequential versus Delayed Sequential Bilateral Cataract Surgery within the Intelligent Research in Sight (IRIS®) Registry Data

Lacy, Megan; Kung, Timothy-Paul H.; Owen, Julia P.; Yanagihara, Ryan T.; Blazes, Marian; Pershing, Suzann; Hyman, Leslie; Gelder, Russell N. Van; Lee, Aaron; Lee, Cecilia S.

doi:10.1016/j.ophtha.2021.07.008

Cited by 41 publications

(43 citation statements)

References 36 publications

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“…Furthermore, the most recent nationwide registry in the US revealed that the rate of endophthalmitis is the same between patients that underwent ISBCS and DSBCS. 22 It is revealing that over half of the patients surveyed in this study indicated that they would accept a higher complication risk for the sake of receiving ISBCS. This factor should be considered when determining the most appropriate technique for each patient.…”

Section: Discussionmentioning

confidence: 77%

Patient Attitudes and Desirability Regarding Immediate Sequential Bilateral Cataract Surgery

Rush¹,

Omoruyi²,

Rush³

2022

OPTH

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Purpose To analyze patient attitudes and desirability regarding routine immediate sequential bilateral cataract surgery (ISBCS). Methods This study was conducted as a prospective, consecutive survey-based case series from a single private practice institution serving a mostly rural population. A standardized phone survey assessing patient perspectives on ISBCS was administered to patients before and after routine delayed sequential bilateral cataract surgery (DSBCS) was performed. Subject responses were analyzed, including a subset analysis on patient responses under a variety of circumstances. Results There were 61 patients enrolled into the study and 47 completed the surveys before and after routine DSBCS (77.0% completion rate). Thirty-nine (83.0%) of respondents had a favorable outlook of ISBCS preoperatively, whereas 36 (76.6%) had a favorable outlook of ISBCS postoperatively (p>0.05). On the postoperative questionnaire, twenty-five (53.2%) of respondents were willing to accept additional surgical risk if necessary to receive ISBCS, and this finding was significant between the subgroup of patients with systemic health co-morbidities compared to those without systemic health co-morbidities (p=0.05). Conclusion Most patients had a favorable outlook of ISBCS before and after undergoing DSBCS. Patients with underlying systemic health co-morbidities were most likely to accept additional surgical risk if necessary to receive ISBCS. From a patient’s perspective, ISBCS may be an acceptable option to routinely implement when cataract surgery is required for both eyes.

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Section: Discussionmentioning

confidence: 77%

Patient Attitudes and Desirability Regarding Immediate Sequential Bilateral Cataract Surgery

Rush¹,

Omoruyi²,

Rush³

2022

OPTH

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“…In the 8 years since its inception [4], the IRIS Registry data has contributed to nearly 40 published studies. Our understandings of the real-world incidences (endophthalmitis after cataract surgery [5], myopic choroidal neovascular membranes [6]), real-world efficacies [pneumatic retinopexy [7], antivascular endothelial growth factor (anti-VEGF) agents for retinal disease [8]] and real-world practice patterns (minimally invasive glaucoma surgery [9], anti-VEGF for diabetic macular edema [10]) in ophthalmology have improved beyond what was previously imaginable. What makes Big Data like the IRIS Registry feel new and ‘real-world’ is that an ever-expanding sample provides an ever-improving approximation of the true population of our nation.…”

Section: Introductionmentioning

confidence: 99%

The evolving field of Big Data: understanding geographic information systems analysis and its transformative potential in ophthalmic research

Soares¹

2022

Current Opinion in Ophthalmology

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Purpose of reviewThe purpose of this review to is to highlight alternative uses of Big Data in the pursuit of ophthalmologic public health. In particular, we highlight geographic information systems (GIS) analysis as a type of Big Data, summarize various GIS methods, and enumerate sources of geographic data. Recent findingsThe recent implementation of the IRIS Registry Data, has expanded our real-world knowledge of ophthalmology in the United States. Such innovations in Big Data allow us to better define ophthalmic diseases, treatments, and outcomes for underserved individuals and subpopulations. One underutilized source of Big Data entails use of geographic information to evaluate geographic heterogeneity and access across the United States. SummaryGIS and Big Data allow for refined epidemiologic estimates of eye disease for specific communities. In particular, how GIS can enable researchers to examine disparities in access to ophthalmic care is reviewed. GIS best practices and some data sources for GIS in ophthalmology are also summarized.

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“…To date, the Analytic Center Consortium has published over 10 major studies in addition to numerous meeting abstracts and paper presentations. 4,[6][7][8][9][10][11][12] The Academy is currently executing the second phase of the IRIS Registry Analytic Center Consortium and has selected additional centers to join the Consortium during this phase.…”

mentioning

confidence: 99%

“…18 A recent study from the IRIS Registry Analytic Center Consortium, "Endophthalmitis rate in immediate sequential vs delayed sequential bilateral cataract surgery within the IRIS Registry data," also highlights the strength of the IRIS Registry where an enormous dataset can be available for a rapid, timely analysis. 7 Lacy et al analyzed the extensive cataract surgery data in the IRIS Registry to compare rates of postoperative endophthalmitis following immediate sequential bilateral cataract surgery (ISBCS) vs delayed sequential bilateral cataract surgery (DSBCS). 7 This was in response to the editorial in Ophthalmology which discussed COVID-19 related challenges in managing surgical patients in ophthalmology just a few months prior that year.…”

mentioning

confidence: 99%

“…7 Lacy et al analyzed the extensive cataract surgery data in the IRIS Registry to compare rates of postoperative endophthalmitis following immediate sequential bilateral cataract surgery (ISBCS) vs delayed sequential bilateral cataract surgery (DSBCS). 7 This was in response to the editorial in Ophthalmology which discussed COVID-19 related challenges in managing surgical patients in ophthalmology just a few months prior that year. 19 Endophthalmitis after cataract surgery is a rare event, and previous studies have relied on much smaller sample sizes, potentially too small to determine accurate endophthalmitis rates following bilateral cataract surgery.…”

mentioning

confidence: 99%

See 1 more Smart Citation

American Academy of Ophthalmology Intelligent Research in Sight (IRIS®) Registry and the IRIS Registry Analytic Center Consortium

Lee

Blazes

Lorch³

et al. 2022

Ophthalmology Science

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This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

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Endophthalmitis Rate in Immediately Sequential versus Delayed Sequential Bilateral Cataract Surgery within the Intelligent Research in Sight (IRIS®) Registry Data

Cited by 41 publications

References 36 publications

Patient Attitudes and Desirability Regarding Immediate Sequential Bilateral Cataract Surgery

Patient Attitudes and Desirability Regarding Immediate Sequential Bilateral Cataract Surgery

The evolving field of Big Data: understanding geographic information systems analysis and its transformative potential in ophthalmic research

American Academy of Ophthalmology Intelligent Research in Sight (IRIS®) Registry and the IRIS Registry Analytic Center Consortium

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