2015
DOI: 10.5301/je.5000209
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Endometriosis: 10 Keys Points for MRI

Abstract: Second- and third-line gemcitabine at a dose of 1,250 mg/m2 on days 1, 8 and 15 every 28 days as a 30-minute i.v. infusion in platinum–taxane resistant EOC is an effective treatment option with a tolerable and manageable toxicity.

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Cited by 8 publications
(6 citation statements)
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References 67 publications
(126 reference statements)
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“…The typical findings are the medialisation of both ligaments (“V” shape appearance) and the focal or global ligament thickening (higher than 6 mm), appearing as hypo- intense image on T1 and T2-W sequences. ( Manganaro et al 2015 ). Other indirect images are less frequently seen ( Table VIII ).…”
Section: Indirect and Atypical Signals According To Anatomical Compar...mentioning
confidence: 99%
“…The typical findings are the medialisation of both ligaments (“V” shape appearance) and the focal or global ligament thickening (higher than 6 mm), appearing as hypo- intense image on T1 and T2-W sequences. ( Manganaro et al 2015 ). Other indirect images are less frequently seen ( Table VIII ).…”
Section: Indirect and Atypical Signals According To Anatomical Compar...mentioning
confidence: 99%
“…33 According to ESUR, basic MR protocol for imaging of endometriosis should include at least two orthogonal T 2 planes (axial and most commonly sagittal), T 1 sequence with and without fat suppression, and optional addition of DWI, contrast-enhanced sequence after Gd injection, susceptibility weighted imaging (SWI) and HASTE sequences. 34 Endometriomas typically show high signal intensity on T 1 images and a "shading" sign on T 2 images, caused by old blood products, which contain extremely high iron and protein concentrations, accompanied by variable restriction of diffusion 35 (Figure 6). Differential diagnosis of endometriomas includes hemorrhagic cysts, which usually have lower signal intensity on T 1 images and absence of a "shading" sign, and cystic teratoma, for which fat suppression is a problem-solving sequence.…”
Section: Imagingmentioning
confidence: 99%
“…Differential diagnosis of endometriomas includes hemorrhagic cysts, which usually have lower signal intensity on T 1 images and absence of a "shading" sign, and cystic teratoma, for which fat suppression is a problem-solving sequence. 35 ( Figure 7)…”
Section: Imagingmentioning
confidence: 99%
“…2 Imaging methods such as transvaginal ultrasound and magnetic resonance allow the precise anatomical localization of some forms of endometriosis. 3,4 Although accurate for ovarian endometrioma and deep infiltrating lesions, these imaging methods are operator-dependent, require a highly specialized training, and fail to detect superficial peritoneal endometriotic implants. 5,6 Decades of research have not led to a reliable biomarker for the non-invasive detection of endometriosis.…”
mentioning
confidence: 99%