Endometrial stromal nodule with smooth muscle differentiation

Vasudevan, Geetha; Rupashree, S; Bhat, Sudha

doi:10.4103/0377-4929.40407

Cited by 5 publications

(3 citation statements)

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“…There is most often a mixed epithelial-myoid phenotype, with immunoreactivity for cytokeratin and actin, and, in some cases, desmin [16]. Immune-stains for EMA are almost always negative.…”

Section: Discussionmentioning

confidence: 99%

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Endometrial Stromal Nodule: Report of a Case

Alaoui

Chaara

Bouguern

et al. 2011

Case Reports in Medicine

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Endometrial stromal nodule (ESN) is the least common of the endometrial stromal tumors. They are rare neoplasms which are diagnosed in most instances by light microscopy. Although such nodules are benign, hysterectomy has been considered the treatment of choice to determine the margins of the tumor required for diagnosis and to differentiate it from invasive stromal sarcoma Whose prognosis is totally different. We report a case of a 45 years old woman, with presurgical diagnosis of adnexal mass or uterine tumor. She underwent a total abdominal hysterectomy. Pathologic examination revealed an endometrial stromal nodule. Through this observation, we insist on the fact that the ESNs are rare and benign entities which must be differentiated from the other invasive malignant stromal tumors; this can change the final prognosis.

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“…There is most often a mixed epithelial-myoid phenotype, with immunoreactivity for cytokeratin and actin, and, in some cases, desmin [16]. Immune-stains for EMA are almost always negative.…”

Section: Discussionmentioning

confidence: 99%

“…In Clement and Scully initial report, three of five patients with followup had recurrences and two died [16]. …”

Section: Discussionmentioning

confidence: 99%

Endometrial Stromal Nodule: Report of a Case

Alaoui

Chaara

Bouguern

et al. 2011

Case Reports in Medicine

View full text Add to dashboard Cite

show abstract

“…In the English published reports, 23 cases of mixed endometrial stromal-smooth muscle tumors including ours have been described, with at least five having circumscribed margins with tumor recurrences. 1,[7][8][9] One may consider that sampling of the tissue in the primary tumors might have been inadequate; however, current diagnostic criteria only using the tumor margin to distinguish between the benign and malignant tumor may always have a problem of underdiagnosis.…”

mentioning

confidence: 99%