Endometrial Growth Factors and Proteins*

Stimulation of endometrium embryo transfer (SEET): injection of embryo culture supernatant into the uterine cavity before blastocyst transfer can improve implantation and pregnancy rates

“…For example, interleukin-1 (IL-1) has been identified as a major factor that modulates the communication between the maternal endometrium and embryo (2)(3)(4). The complete IL-1 system in human embryos has been detected at all developmental stages (16).…”

“…The embryo produces several factors during its development to signal its presence to the maternal organism, and several of these embryonic factors that modulate endometrial receptivity have been detected in embryo culture supernatant (2)(3)(4)(5)(6)(7)(8).…”