Encircling the Tendon Repair Site with Collagen-GAG Reduces the Formation of Postoperative Tendon Adhesions in a Chicken Flexor Tendon Model

Autologous venous grafting promotes healing and reduces adhesion formation in experimentally severed canine superficial digital flexor tendons

“…There has been considerable research conducted in the past in an effort to better understand the biological response of tendon injury and to improve the outcome of surgical technique performed (Amadioet al, 1988;Lilly & Messer, 2006;Bhavsar & Shettko, 2010). A plethora of techniques and materials have been utilised to overcome such complications using synthetic or natural products (Lilly & Messer, 2006;Bhavsar & Shettko, 2010).…”

“…A plethora of techniques and materials have been utilised to overcome such complications using synthetic or natural products (Lilly & Messer, 2006;Bhavsar & Shettko, 2010). In dogs, an autologous venous graft obtained from the external jugular vein showed substantially reduced adhesion formation (Bins Ely et al, 1999).…”

An Experimental Study on the Effect of Safflower Yellow on Tendon Injury-Repair in Chickens

“…Flexor digit tendons in Leghorn chickens are similar to that of humans and are divided into shallow and deep ones. They possess a sheathing canal, interdigit joints on flexion near the side of the shallow tendon and ones on the flexion distal side of the deep tendon [11], and some previous studies mainly used the flexor digitorum profundus tendon model of Leghorn chicken [11][12][13][14]. Therefore, the present study used a flexor digit tendon injury-repair model in Leghorn chicken to examine tendon biomechanics, histopathology, and the expression of bFGF and collagen type I protein following injury, and the benefit of SY in the process of tendon injury-repair.…”

The effect of a collagen-elastin matrix on adhesion formation after flexor tendon repair in a rabbit model

“…All of these factors reduce tendon glide and encourage adhesion formation. Multiple materials and pharmacologic agents have been experimented to minimize peritendinous scaring and provide a flexor sheath, some with promising results [11][12][13][14][15][16][17][25][26][27][28][29][30]. Nevertheless, none of these substances have found their way into clinical practise yet.…”

“…Various agents have been investigated for the prevention of these adhesions [10][11][12][13][14][15][16][17]. None of them has found its way into routine clinical use.…”