Enantiomer separation of propranolol and tryptophan using bovine serum albumin functionalized silica nanoparticles as adsorbents

Li, Wei; Ding, Guoyu; Tang, An‐Na

doi:10.1039/c5ra17535f

Cited by 28 publications

(21 citation statements)

References 37 publications

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“…Using Trp as a model compound, some main factors that could affect the enantioselective adsorption, including adsorption equilibrium time, pH of the sample solution, the amount of adsorbents, and the cycles of adsorption process , were systematically investigated. The adsorption experiment for each factor was repeated for three times.…”

Section: Resultsmentioning

confidence: 99%

“…As is well known, the adsorption equilibrium time is considered to be an important factor in the adsorption process . Experimental data (Fig.…”

Section: Resultsmentioning

confidence: 99%

“…To evaluate the reusability of the chiral sorbents, the enantioseparation of initial Trp solution was performed using the same batch of Fe 3 O 4 @PDA@TE MPs. Notably, these used MPs could be readily regenerated by washing with PBS solution (30 mM, pH 8.5) and water by ultrasonication . As shown in Supporting Information Fig.…”

Section: Resultsmentioning

confidence: 99%

“…The enantiomeric excess (%, e. e.) is an index to characterize chiral recognition ability. The value of % e. e. can be calcula‐ted with the following equation,

%, normale . e . = \frac{[R] - [S]}{[R] + [S]} \times 100 %,

where [ R ] and [ S ] represent the respective concentration of two enantiomers, and in chromatographic analysis, the values of [ R ] and [ S ] can be characterized by time corrected peak areas (peak area/ t m ) .…”

Section: Methodsmentioning

confidence: 99%

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Facile synthesis and application of teicoplanin‐modified magnetic microparticles for enantioseparation

et al. 2017

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A facile, mild method for the preparation of teicoplanin (TE) modified Fe O microparticles (MPs) employing polydopamine (PDA) layer as a versatile secondary reaction platform was developed. The synthesized magnetic MPs (Fe O @PDA@TE) were characterized by various characterization techniques, such as TEM, zeta potential etc, to affirm the successful modification of TE to magnetic Fe O MPs. Using the as-synthesized materials as chiral adsorbents, efficient chiral separation of representative racemic compounds was successfully achieved. Due to the magnetic responsivity, the materials were easily isolated from the racemic solutions under an external magnetic field and could be readily reused for at least three times. Thus, the well-prepared functional magnetic MPs have great potential in preparative chiral separation.

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Section: Resultsmentioning

confidence: 99%

“…As is well known, the adsorption equilibrium time is considered to be an important factor in the adsorption process . Experimental data (Fig.…”

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

“…The enantiomeric excess (%, e. e.) is an index to characterize chiral recognition ability. The value of % e. e. can be calcula‐ted with the following equation,

%, normale . e . = \frac{[R] - [S]}{[R] + [S]} \times 100 %,

Section: Methodsmentioning

confidence: 99%

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Facile synthesis and application of teicoplanin‐modified magnetic microparticles for enantioseparation

et al. 2017

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“…During the period 2014–2016, only two publications recorded the use of α‐CD , while no separations were reported by the use of γ‐CD. α‐CD was used as a CS for the estimation of tryptophan enantiomeric excess . However, it is important here to note that, when conventional CE is used for enantiomeric excess measurements, two main issues have to be considered.…”

Section: Chiral Selectorsmentioning

confidence: 99%

Chiral selectors in CE: Recent development and applications (mid‐2014 to mid‐2016)

Stavrou

Agathokleous

Kapnissi‐Christodoulou

2017

Electrophoresis

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This report, which is a sequence of a series of reviews, records the most important chiral selectors (CSs) applied in CE. It highlights the CSs that were used during the period 2014 to mid-2016. In this review, method developments, validations, and pharmaceutical along with biomedical applications are presented. The different CSs include CDs, antibiotics, cyclofructants, linear and branched oligo- and polysaccharides, and polymeric surfactants. In addition, the advantages of these CSs, along with their chiral recognition mechanisms, and their performance, are discussed.

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Versatile Surface Modification Using Polydopamine and Related Polycatecholamines: Chemistry, Structure, and Applications

Barclay

Hegab

Clarke

et al. 2017

Adv Materials Inter

293

223

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Almost ten years ago, Lee et al. [13] formulated a universal adhesive coating based on observation of the strong attachment by mussels through their byssal threads to virtually all types of inorganic and organic surfaces. The amino acid compositions of the mussel foot proteins that generate the attachment are rich in catechol and amine groups. [13][14][15] These groups associate under marine conditions, forming strong covalent and noncovalent interactions with substrates. [13] This led to the idea that both catechol and amine groups were crucial in forming robust, wide spectrum adhesive nanolayers [16,17] and consequently dopamine was conceived as a powerful building block for spontaneous deposition of thin polymer films. The dopamine monomer is deposited onto unadulterated surfaces through self-assembly and oxidative cross-linking from mild pH aqueous solution in a rapid reaction. This results in a durable, nanoscale, conformal, and hydrophilic coating that can be readily modified to introduce specific surface chemistries for a particular application. [18][19][20][21][22] These bioinspired, polydopamine materials are chemically and structurally indistinguishable from eumelanins found in the human body, [23,24] providing excellent biocompatibility. Additionally, polydopamine has broad electromagnetic absorption and excellent photothermal energy conversion [25] as well as having ionic-electronic hybrid conductivity. [26] Along with the excellent coating performance, these properties provide a vast array of potential applications for polydopamine materials.In this article, we explain what is known about polydopamine and related catecholamine coatings; their formation, the adhesion mechanism, and their physicochemical properties and we also review the applications of these materials (Figure 1). Since 2011, there have been a number of reviews on this subject matter, including general reviews on the physicochemical properties of polydopamine coatings [11,20,[27][28][29] and their applications. [20,27,30] There are also a number of more specific reviews on the chemical synthesis and modulation of polycatecholamine coatings, [31] the biomedical applications of these coatings, [8,[32][33][34] their electronic properties, [26,35] the use of polydopamine to make films at fluid interfaces, [36] in hierarchically constructed particles, [33] and capsules, [30] exploitation of polycatecholamine coatings in membrane filtration, [37] polydopamine-derived carbon materials, [38] and the use of coordination chemistry in catechol-based materials. [39] Nonetheless, this area of research is growing so rapidly [25,27] that many recent Polydopamine and related polycatecholamines can be easily deposited onto almost any surface from mild, aqueous solution. This results in durable, nanoscale coatings that exhibit high biocompatibility and have useful chemical and electronic properties. Additionally, these materials can be readily chemically and physically modified, and consequently, they are used extensively for surface modification. This ...

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Enantiomer separation of propranolol and tryptophan using bovine serum albumin functionalized silica nanoparticles as adsorbents

Abstract: The immobilization of popular chiral selectors on the surface of nanomaterials to prepare new chiral adsorbents for preparative chiral separation is a research hotspot in separation science nowadays.

Cited by 28 publications

References 37 publications

Facile synthesis and application of teicoplanin‐modified magnetic microparticles for enantioseparation

Facile synthesis and application of teicoplanin‐modified magnetic microparticles for enantioseparation

Chiral selectors in CE: Recent development and applications (mid‐2014 to mid‐2016)

Versatile Surface Modification Using Polydopamine and Related Polycatecholamines: Chemistry, Structure, and Applications

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