Enamel Maturation

Molar-incisor hypomineralization: Therapeutic challenge to paediatric dentistry practice

“…Zvaničnih podataka o rasprostranjenosti MIH za našu zemlju nema, mada se procenjuje da iznosi oko 19,5% 7,8 . Osnovni patogenetski mehanizam MIH je poremećaj resorptivnog potencijala ameloblasta i inhibicija proteolitičkih enzima usled čega dolazi do zadržavanja gleđnih proteina, ometanja rasta kristala i maturacije gleđi [9][10][11][12][13][14] . Rezultat toga je promena u mineralnom sastavu gleđi, povećanje poroznosti, smanjenje tvrdoće i modula elastičnosti hipomineralizovane gleđi u odnosu na gleđ koja nije zahvaćena promenama, što se klinički manifestuje promenama u boji gleđi, koje variraju od beličastih do promena braon prebojenosti [15][16][17] .…”

“…There are no official data on the prevalence of MIH for our country, but it is estimated to be approximately 19.5% 7,8 . The main pathogenic mechanism of MIH is the disorder of adsorbent potential of ameloblasts and inhibition of proteolytic enzymes, causing retention of enamel proteins, interfering with crystal growth and maturation of enamel [9][10][11][12][13][14] . This results in the transformation of mineral composition of the enamel, increase in porosity, decrease in hardness and elasticity module of hypomineralized enamel compared to the nonaffected enamel, which is clinically manifested by changes in enamel colour that varies from whitish to changes of brown discoloration [15][16][17] .…”

Crystallographic Study of the Immature Bovine Incisor Enamel and Dentin

“…The incident X-ray beam passed a slit to use the peak intensity, monochromatized by a graphite crystal, then irradiated to the sample box. Thin sectioned sample was placed in the sample , Hiroyuki Okada 1) , Takao Kuwada-Kusunose 2) , Kunihiro Suzuki 2) , Hiroya Gotouda 3) and Toshiro Sakae 1) Abstract: The aim of this study was to clarify the relation between calcification and crystallization occurring in the immature bovine enamel and dentin. The calcification process was semi-quantified using monochromatic X-ray microradiography and expressed as pseudo-color mapping for the polished thin sections.…”

“…Although it was well known that the calcification mechanism of tooth enamel [1][2][3][4] completely differs from that of dentin 5,6) , the details of these calcification mechanisms have not been clarified yet. The difficulties of promoting these studies located at that these materials in focus are the complexes of the inorganic and the organic components; the former being the biological apatite 7) and the latter being collagen in dentin 8) and some particular proteins in enamel 9) .…”

Molar incisor hypomineralization: An update

“…These alterations result in protein retention, particularly amelogenin, leading to interference with crystal growth and enamel maturation. [8] Although MIH is considered to be idiopathic defect clear etiology is not yet agreed upon. Risk factors associated with MIH can be divided into prenatal, perinatal, and post-natal factors [ Table 1].…”