Emerging theranostic gold nanostructures to combat cancer: Novel probes for Combinatorial Immunotherapy and Photothermal Therapy

Magnetic nanocarriers adorned on graphene: promising contrast-enhancing agents with state-of-the-art performance in magnetic resonance imaging (MRI) and theranostics

“…In continuation of our research work on the diverse applications of nanomaterials in the biomedical arena, [16][17][18][19][20][21][22][23][24][25][26] the recent advances of graphene-based magnetic nanocarriers as potential MRI contrast agents are summarized comprising assorted methods for the preparation of GO as well as graphene-based nanocomposites. The prominent features and magnetism of various graphenebased novel MRI contrast agents are presented in Table 1, along with brief coverage on their theranostic applications and cytotoxicity aspects to assess their biocompatibility.…”

Gold Nanoparticles Contact with Cancer Cell: A Brief Update

“…The overexpression of sialic acid-rich regions in cancer calls [ 118 ] can contribute to the creation of a negative charge on cell surfaces which, in turn, increases their interaction with positive charged AuNPs [ 119 ]. Many other types of molecules, (i.e., rifampicin, cytosine-phosphate-guanine oligonucleotides, and amphiphilic drugs such the small molecule Toll-like receptor agonist resiquimod (R848)) have recently been used to functionalize AuNPs in order to increase their target specificity, cellular uptake rate, immune stimulation and therapeutic properties [ 120 , 121 , 122 ]. Despite a vast number of scientific papers confirming the important role of the surface functionalization with specific ligands as strategy to improve biocompatibility both in vitro and in vivo, and so to allow for the development of high precision therapy and/or diagnosis, a recent review by Goddard et al has highlighted that each targeting ligand has both benefits and drawback and argued that it is necessary to make comparisons between different targeting modalities for the same receptor to establish the most effective targeting approach [ 38 ].…”

One-Pot Synthesis of Silica-Coated Gold Nanostructures Loaded with Cyanine 5.5 for Cell Imaging by SERS Spectroscopy

“…Loading the shell with anticancer chemicals or specific oligonucleotide inhibitors is favorable for targeted chemotherapy of cancer with reduced side effects [ 17 , 18 , 19 ]. Gold nanoparticles with a shell, including specific antigens or immune-stimulating agents, are advantageous for immunotherapy of cancer [ 20 ].…”