Emergence characteristics of sevoflurane compared to halothane in pediatric patients undergoing bilateral pressure equalization tube insertion

Cravero, Joseph P.; Beach, Michael L.; Dodge, Carter P.; Whalen, K.

doi:10.1016/s0952-8180(00)00180-x

Cited by 73 publications

(65 citation statements)

References 14 publications

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“…Also, period of stay in PACU was lesser in patients who did not have EA in all 3 groups, when compared to those who had EA. This was in contrast to several studies which documented that time to reach discharge criteria was unchanged by the addition of either small dose of fentanyl 14 and ketamine…”

Section: 617contrasting

confidence: 99%

“…Cohen EA et al 13 found concurrent use of fentanyl during induction with sevoflurane in a dose of 2.5mcg/kg resulted in a low incidence of EA in children receiving sevoflurane or desflurane anaesthesia. Cravero et al 14 showed that addition of fentanyl 1mcg/kg 10 min before discontinuation of sevoflurane decreased incidence of postoperative agitation from 56% to 12% in children scheduled for magnetic resonance imaging scans without any surgical intervention.…”

Section: Kararmaz Et Almentioning

confidence: 99%

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Emergence agitation in children after sevoflurane anaesthesia: a comparative evaluation of ketamine and varying doses of fentanyl

Thomas¹,

Lagoo

Kilpadi³

2015

Sri Lankan J Anaesthesiol

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Introduction:Sevoflurane, inhalational anaesthetic of choice in children, is associated with high incidence of emergence agitation (EA). But that "one drug" which can significantly reduce or prevent EA still eludes us. Thus we aimed at studying the efficacy of intravenous ketamine and varying doses of intravenous fentanyl on postoperative emergence agitation in children receiving sevoflurane anaesthesia. Materials and methods:This prospective, double blind, randomized comparative study was conducted on 114 children, 2-10 years, with ASA physical status I-II. They were undergoing herniotomy under sevoflurane anaesthesia and were randomly divided into Group A receiving ketamine 0.5 mg/kg, Group B fentanyl 2mcg/kg and Group C fentanyl 3mcg/kg at the time of induction. Postoperatively emergence agitation was assessed every 5 min during first 60 min of PACU stay using Aono's four point scale. We also observed recovery characteristics including time to extubation, time to emergence, discharge from PACU and postoperative complications. Results: The incidence of EA was significantly low in Group A (31.6%) and Group C (28.9%) compared to group B (65.8%), with no significant difference between Group A and Group C. Incidence of EA was higher in preschool children. A prolonged PACU stay was observed in all children who developed EA, with lesser duration of PACU stay noted in fentanyl 3 mcg/kg group. Conclusion: Intravenous administration of either ketamine 0.5 mg/kg or fentanyl 3mcg/kg i.v. at the time of induction reduces the incidence of EA effectively when compared with fentanyl 2mcg/kg, without delaying recovery.

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Section: 617contrasting

confidence: 99%

Section: Kararmaz Et Almentioning

confidence: 99%

Emergence agitation in children after sevoflurane anaesthesia: a comparative evaluation of ketamine and varying doses of fentanyl

Thomas¹,

Lagoo

Kilpadi³

2015

Sri Lankan J Anaesthesiol

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“…In several studies agitation has been reported in people after anesthesia (29,30); however, Matthews et al (31) reported no complications in various animal species such as horse. Likewise, we did not find such complications in Angora goats.…”

Section: Discussionmentioning

confidence: 99%

Comparison of sevoflurane and isoflurane effects on cardiovascular andrespiratory system during spontaneous ventilation in Angora goats

Kumandaş¹,

Elma²

2015

Turk J Vet Anim Sci

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IntroductionIsoflurane and sevoflurane are noncombustible halogenated anesthetic agents. In addition to a faster anesthesia induction and shorter recovery time, isoflurane also provides good muscle relaxation. Sevoflurane is more preferable than isoflurane because it has lower irritation of the respiratory tract than isoflurane and it has some advantages such as easy induction and a fast recovery compared to isoflurane (1-3).Propofol, a nonbarbiturate derivative, is a sedative and hypnotic drug that can be used in small animals for anesthesia and maintenance of sedation. Due to its shorter half-life and absence of accumulation in the body (4-6), it can be used safely in animals such as small ruminants (4,7). Information of the possible side effects of these types of anesthetics on small ruminants, however, is not present yet (8)(9)(10)(11)(12).Goats are preferred as an animal model in experimental studies such as orthopedic, cardiovascular, respiratory, and cerebrovascular studies (13-15). Sevoflurane, isoflurane, and halothane are often used as anesthetic agents. However, anesthetic requirements have not been determined in the goat for these agents accurately. Therefore, the aim of this research was to compare the anesthetic effects of two different inhalation anesthetics that are used in the maintenance of anesthesia with propofol medication. Materials and methodsThe study was approved by the Animal Research Local Ethics Committee of Kırıkkale University (Decision No: 70/09). Seven healthy adult female Angora goats were used in this study. Prestudy screening included a physical examination and complete blood count to ensure animals were in good health. The same goats were used for both anesthesia groups within a 2-week interval. Once anesthesia was induced with propofol, it was maintained either with isoflurane or sevoflurane.Feed and water were withheld from animals 18 h and 2 h prior to anesthesia respectively in order to prevent ruminal tympani during anesthesia. The medial auricular artery was catheterized (Wellcath-x plus 22G, Vellmed, Turkey) to measured systolic arterial pressure (SAP), diastolic arterial pressure (DAP), and mean arterial pressure (MAP). The caudal auricular vein was Abstract: Seven healthy Angora goats were used to compare the effects of isoflurane and sevoflurane on the cardiovascular and respiratory systems during anesthesia periods. Once anesthesia was induced with propofol at 5.1 ± 0.9 mg/kg, it was maintained with isoflurane at 1%-3% in the first treatment period and sevoflurane at 2%-4% in the second treatment period after a 15-day interval. Heart rates measured immediately after anesthesia induction and 5 min later were found to be statistically significant between anesthetic groups (P < 0.05). Mean blood pressure in the isoflurane group decreased (75.7 ± 7.2 to 59.8 ± 9.8 mmHg) (P < 0.05) throughout the anesthesia period. It was determined that respiratory rate in sevoflurane treatment was lower than that in isoflurane treatment. In terms of time to stand up, sevoflurane-adminis...

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“…As a potent bronchodilator, sevoflurane is a safe agent for individuals with asthma and reactive airway disease. Compared to halothane, sevoflurane has a significantly higher incidence of delirium and agitation in children, 26 requiring intervention to improve the quality of recovery.…”

Section: Sevofluranementioning

confidence: 99%

An overview of anesthetic procedures, tools, and techniques in ambulatory care

Messieha

2015

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Ambulatory surgical and anesthesia care (ASAC), also known as Same Day Surgery or Day Care in some countries, is the fastest growing segment of ambulatory surgical and anesthesia care. Over 50 million ambulatory surgical procedures are conducted annually comprising over 60% of all anesthesia care with an impressive track record of safety and efficiency. Advances in ambulatory anesthesia care have been due to newer generation of inhalation and intravenous anesthetics as well as airway management technology and techniques. Successful ambulatory anesthesia care relies on patient selection, adequate facilities, highly trained personnel and quality improvement policies and procedures. Favoring one anesthetic technique over the other should be patient and procedure-specific. Effective management of post-operative pain as well as nausea and vomiting are the final pieces in assuring success in ambulatory anesthesia care.

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Emergence characteristics of sevoflurane compared to halothane in pediatric patients undergoing bilateral pressure equalization tube insertion

Cited by 73 publications

References 14 publications

Emergence agitation in children after sevoflurane anaesthesia: a comparative evaluation of ketamine and varying doses of fentanyl

Emergence agitation in children after sevoflurane anaesthesia: a comparative evaluation of ketamine and varying doses of fentanyl

Comparison of sevoflurane and isoflurane effects on cardiovascular andrespiratory system during spontaneous ventilation in Angora goats

An overview of anesthetic procedures, tools, and techniques in ambulatory care

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