Elusidasi Awal Daya Hambat Ekstrak Etanol Daun Ketapang  (Terminalia Catappa L.) Terhadap Pertumbuhan Staphylococcus Aureus  ATCC25923 Penyebab Gingivitis

Purwaningsih, Putu Pande; Darmayasa, Ida Bagus Gede; Astiti, Ni Putu Adriani

doi:10.24843/metamorfosa.2020.v07.i01.p08

Cited by 2 publications

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“…Beberapa penelitian menunjukkan bahwa ekstrak daun sirsak (Annonamuricata Linn), ekstrak daun kedondong hutan (Spondias pinnata), dan ekstrak daun dewa (G.pseudochina) efektif menurunkan jumlah koloni Candida albicans pada plat resin akrilik heat-cured. [11][12][13] Penggunaan bahan herbal tradisional semakin banyak digunakan sebagai alternatif pengganti bahan kimia karena harga yang lebih murah, bahan mudah didapat, serta memiliki efek samping relatif kecil. 14,15 Daun mangga (Mangifera indica L.) merupakan salah satu tanaman yang dapat digunakan karena mengandung senyawa polifenol, mangiferin, triterpenoid, alkaloid, flavonoid, stereoid, polifenol serta tanin yang berpotensi sebagai antijamur.…”

Section: Pendahuluanunclassified

Efektivitas Ekstrak Daun Mangifera indica L. Menghambat Candida albicans pada Plat Resin Akrilik Heat-cured

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Lestarini

2023

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Heat-cured acrylic resin dentures are used to treat tooth loss, however, pores are easily formed on their surfaces which make it easier for Candida to adhere. Improper maintenance of dentures can cause overgrowth of Candida albicans and trigger denture stomatitis. This study aimed to determine the effectiveness of Mangifera indica L. extract on inhibition of Candida albicans on heat-cured acrylic resin plates. This was a true experimental laboratory study with a post-test only control group design. Samples were heat-cured acrylic resin plates contaminated with Candida albicans. The treatment groups were chlorhexidine gluconate 0.2%, aquades, and extract with concentrations of 65%, 75%, 85%, and 100%. Samples were immersed in the treatment groups for 15 minutes, followed by dilution and culture on SDA media, and then fungal colonies were observed. Data were analyzed with the Shapiro-Wilk normality test, the Levene's test for homogeneity, continued with the parametric one-way ANOVA and post hoc least significant difference tests. The results showed significant differences between the treatment groups (p<0.05). The percentage of the extract group with the lowest number of fungi was 75%, meanwhile the highest one was 65%. In conclusion, Mangifera indica L. leaf extract is effective in inhibiting the growth of Candida albicans on heat-cured acrylic resin plates with an optimal concentration of 75%. Keywords: mango leaf extract (Mangifera indica L.); Candida albicans; heat-cured acrylic resin Abstrak: Gigi tiruan resin akrilik heat-cured digunakan untuk mengatasi kehilangan gigi, namun sering terbentuk porus pada permukaannya yang mempermudah perlekatan Candida. Pemeliharaan gigi tiruan yang tidak tepat dapat menyebabkan pertumbuhan Candida albicans berlebihan dan memicu terjadinya denture stomatitis. Penelitian ini bertujuan untuk mengetahui efektivitas ekstrak daun mangga arum manis (Mangifera indica L.) dalam menghambat Candida albicans pada plat resin akrilik heat-cured. Jenis penelitian ialah true experimental laboratory dengan post test only control group design menggunakan sampel plat resin akrilik heat-cured yang dikontaminasi Candida albicans. Kelompok perlakuan yaitu chlorhexidine gluconate 0,2%, akuades, ekstrak konsentrasi 65%, 75%, 85%, dan 100%. Sampel direndam pada kelompok perlakuan selama 15 menit, dilanjutkan dengan tahap dilusi serta kultur pada media SDA, diakhiri dengan pengamatan koloni jamur. Analisis data menggunakan uji normalitas Shapiro Wilk, uji homogenitas Levene, dan dilanjutkan dengan uji parametrik One-Way ANOVA, dan Post Hoc Least Significant Difference. Hasil penelitian mendapat-kan perbedaan bermakna antar kelompok perlakuan (p<0,05). Kelompok ekstrak dengan angka jamur terendah ialah konsentrasi 75% dan yang tertinggi ialah konsentrasi 65%. Simpulan penelitian ini ialah ekstrak daun mangga arum manis (Mangifera indica L.) efektif dalam menghambat pertumbuhan Candida albicans pada plat resin akrilik heat-cured dengan konsentrasi optimal 75%. Kata kunci: ekstrak daun Mangifera indica L.; Candida albicans; resin akrilik heat-cured

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Section: Pendahuluanunclassified

Efektivitas Ekstrak Daun Mangifera indica L. Menghambat Candida albicans pada Plat Resin Akrilik Heat-cured

Purbasari

Susanti

Lestarini

2023

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“…separating the fractions for polar, semi-polar and nonpolar compounds. The purpose of fractionation is to separate the components of the active compound from the resulting extract (Purwaningsih et al, 2020). In this study, the polar solvent for the fractionation used water, while for semi-polar solvent used ethyl acetate; and a non-polar solvent with hexane.…”

Section: B Semi-polarmentioning

confidence: 99%

Chemical Compound of Terminalia Catappa L. as Hemostatic Agents in Post Tooth Extraction

Sirat¹,

Senjaya²

2021

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Terminalia catappa L. is one of the herbal plants that contain flavonoids that play a role in wound healing including to bleeding after tooth extraction. The aim of our study was to identify the chemical compounds contained in Terminalia catappa L. leaves. This type of research was experimental. The sample in this study was the leaves of Terminalia catappa number 3-6 from the base, at a tree height of 6 meters picked as much as 6 kilograms. Data analysis qualitatively and quantitatively. The highest content in ethanol extract of Terminalia catappa L of saponins and alkaloids were fractioned with distilled water and the lowest content were fractioned with hexane. Meanwhile distilled water is also used to fractioned the highest content of tannins and phenol. While ethyl acetate was used to fractioned the lowest content of tannins and the highest content of flavonoid. The lowest flavonoid in distilled water extract was fractioned using hexane. For the lowest content of phenol was fractioned using hexane. The results show the highest content of saponins is 3,787.80 mg/100g, the lowest is 166.67 mg/100g. The highest content of Alkaloids is 1,798.57 mg/100g, and the lowest is 576.80 mg/100g. The highest content of tannins is 53,140.72 mg/100g, the lowest is 8,391,803 mg/100g. The highest content of flavonoids is 2,5964.14 mg/100g, the lowest flavonoid is 462.84 mg/100g. The highest content of phenol 29,968.05 mg/100g, the lowest is 225.46 mg/100g. The highest antioxidant activity with AAI (Antioxidant Activity Index) obtains value of 0.36. This shows the moderate antioxidant ability. Terminalia catappa L. contain saponins, alkaloids, tannins, flavonoids, and triterpenoids. The active compound of Terminalia catappa L will generally be produced optimally if a polar solvent is used.

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Elusidasi Awal Daya Hambat Ekstrak Etanol Daun Ketapang (Terminalia Catappa L.) Terhadap Pertumbuhan Staphylococcus Aureus ATCC25923 Penyebab Gingivitis

Cited by 2 publications

References 1 publication

Efektivitas Ekstrak Daun Mangifera indica L. Menghambat Candida albicans pada Plat Resin Akrilik Heat-cured

Efektivitas Ekstrak Daun Mangifera indica L. Menghambat Candida albicans pada Plat Resin Akrilik Heat-cured

Chemical Compound of Terminalia Catappa L. as Hemostatic Agents in Post Tooth Extraction

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