Electrospun composites of PHBV, silk fibroin and nano-hydroxyapatite for bone tissue engineering

Silk as a potential candidate for bone tissue engineering

“…Applying 2 wt% ceramic and 2 wt% SF improved the Young's modulus of the scaffold compared to that of the pure polymeric matrices. Consistent with the results of this study, the authors reported that increasing the ceramic content to 5 wt% decreased the modulus [170].…”

Repairing rabbit radial defects by combining bone marrow stroma stem cells with bone scaffold material comprising a core-cladding structure

“…Bone tissue engineering primarily consists of three major factors. The bone scaffold material is the most critical factor in bone tissue engineering because it serves as a carrier of seed cells and active factors, and provides support for the formation of new bones (Kang and Cho, 2012;Paşcu et al, 2013). Proper structure, appropriate physical properties, and excellent biocompatibility are the most important requirements of an ideal bone scaffold material.…”

Design of biocomposite materials for bone tissue regeneration

“…It has longer degradation time than P3HB. Nanofibrous scaffold of PHBV-nHA prepared by electrospinning using silk fibroin, displayed improved bioactivity and cell attachment than PHBV scaffold [74]. Silk fibroin is a protein polymer derived from silkworm, Bombyx mori.…”