Electrophysiological status of sural nerves in type 2 diabetes mellitus patients before symptomatic peripheral neuropathy

Panta, Raju; Thakur, Dilip; Paudel, Bishnu Hari

doi:10.5603/dk.2017.0021

Cited by 1 publication

(2 citation statements)

References 16 publications

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“…Amina Zaidi et al, in their study, explored the correlation between Duration of diabetes and SNCS parameters of Median, Ulnar, Sural and Superficial peroneal nerves; and a significant negative correlation (p<0.05) was found. [13] Similar findings were found by Raju Panta et al 2017, Ahsan Numan et al 2021, [11,12] On the contrary, Pastore C et al, 1999 and Senhamil et al, 2021 did not find any significant difference in the nerve conduction attributes in type-II Diabetic individuals with dissimilar duration of diabetes. [24,25] In conformity with the previous studies on Sural nerves in Diabetic individuals, the current study suggests that Diabetic nerves become more liable to lesion as the duration of Diabetes increases.…”

Section: Pathogenesis Of Diabetic Neuropathysupporting

confidence: 62%

“…Very few studies have been undertaken to study the correlation and effect of Duration of diabetes and Nerve conduction study parameters. [11][12][13][14] Hence, the aim of the present study is to study the effect of duration of diabetes on Sural nerve conduction parameters in type-II Diabetes Mellitus. Nerve conduction velocity (NCV) and Sensory Nerve Action Potential (SNAP) amplitude of Bilateral Sural nerves were the parameters to be studied.…”

Section: Introductionmentioning

confidence: 99%

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Effect of Duration of Diabetes on Sural Nerve Conduction Parameters in Subjects with Type-II Diabetes Mellitus - A Cross sectional Comparative Study

Pattni

Prajapati²

2022

Int J Health Sci Res

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Background: Diabetes mellitus has become a rapidly rising global health-care problem in the recent decades. Amongst the wide spectrum of concurrent complications, Diabetic peripheral neuropathy (DPN) is quite common and distressing. The sensory symptoms may vary from numbness, hypo-aesthesia, allodynia to severe paresthesia. Long term consequences of these sensory disturbances are foot ulceration, imbalance, increased risk of fall and even amputations too. Since these symptoms interfere with the quality of life of diabetic individuals and also lead to increased socio-economic burden, immediate action to combat these is pre-requisite for health care development of any nation. Further, if timely diagnosed, these complications can largely be prevented. Nerve conduction study holds the gold standard tool to detect Diabetic neuropathy at its subclinical stage itself. Sural nerve is the commonest and most prevalent nerve involved, so it was considered for analysis. Duration of diabetes is an important factor which affects neurophysiology. Thus, the aim of the present study is to study the effect of duration of diabetes on Sural nerve conduction parameters in subjects with type-II Diabetes Mellitus having varying duration of diabetes. Method: Seventy-three Subjects with type-II Diabetes mellitus were divided into three groups according to the duration of disease. Group A:<5 years, B: 5-10 years, C: >10 years of diabetes. Bilateral Sural nerves were analysed using RMS EMG SALUS machine. Result: Significant reduction of Sensory nerve action potential (p<0.05) was found as the duration of diabetes increased from Group A to C. Conclusion: Long term Diabetes leads to Axonal degeneration in Sural nerves. Key words: Diabetic peripheral neuropathy, Nerve conduction study, Sural nerves, Diabetes mellitus, Duration of Diabetes, Axonal degeneration.

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Section: Pathogenesis Of Diabetic Neuropathysupporting

confidence: 62%