Electron Impact Mass Spectra With Supercritical Fluid Chromatography/Mass Spectrometry

Abstract

An SFC/MS system has been constructed through additions and appropriate modifications to a GC/MS instrument. Supercritical fluid conditions were effected by transport of liquid carbon dioxide mobile phase through a micro pump to the injector and then into a fused silica capillary column.Two approaches to a successful coupling of the resultant effluent to the GC/MS system in order to yield El mass spectra have been demonstrated. In one configuration, an open-split GC/MS interface was used to eliminate excess mobile phase.Inside the heated interface was a frit restrictor connected to a deactivated, uncoated fused silica capillary column (also heated) which functioned as a transfer line into the ion source. An alternate configuration omitted the open-split interface and located the frit restrictor inside the ion source. A 99 Copyright© 1990 by Maicel Dekker, Inc.