Dynamic behaviour of a micro-cantilever beam under periodic electro-thermal loading is studied in this paper. For certain applications the beam is required to vibrate at a particular frequency. Modal analysis using 3D finite element is used in order to find the geometrical parameters that makes fundamental frequency of the beam match the required frequency. Then non-linear dynamic thermoelastic analysis is conducted on the system to analyse the time-history (transient) behaviour of the beam and record its tip displacement. However, due to uncertainties and non-repeatabilities that are inherent properties of the system along with those associated with the manufacturing, final product is likely to have deviations from these estimated values (fundamental frequency and tip displacement). Thus, choosing a nominal (desired) design and studying the deviation in natural frequency and tip displacement via 2 k factorial Design-of-Experiments (DOE), effect of uncertainties on the overall performance of the system is investigated. This allows finding the significance of individual parameters on the overall robustness of the design as well as potential interactions between various parameters. Finally, the expected behaviour of the micro-cantilever and its robustness to design and implementation uncertainties are elaborated and statements for robust design of this system are made.