Electrochemical Sensing of Catecholamines at the Water/ 1,6‐Dichlorohexane Interface

Abstract

In this work, the analytical use of facilitated ion transfer of catecholamines by dibenzo-18-crown-6 was investigated at the water/1,6-dichlorohexane interface using electrochemical methods (cyclic and square wave voltammetry). The experimental conditions for the analytical determination of noradrenaline and dopamine were established and detection limits of 1.7 and 0.35 mM were obtained, respectively. The effect of excess ascorbic acid on the transfer and detection of the two catecholamines was investigated. The selectivity coefficients obtained for dopamine and noradrenaline in the presence of ascorbic acid were 3.5 10 À4 and 2.5 10 À3 , respectively.

Ion-transfer voltammetric determination of folic acid at meso-liquid–liquid interface arrays

“…S10) and the method reported previously on the selectivity of amperometric sensors. [64][65][66] It was found that the values of the selectivity coefficients are relatively low, which demonstrates that such a HMSM-CTAB-supported organogel electrode can be potentially applied as an amperometric sensor for the detection of anionic FA although it is possible that some hydrophilic anions at high concentrations in the practical samples may interfere with the direct determination of FA in aqueous solution under physiological conditions. In order to further examine the practical application of the detection method for FA as proposed in this study, a kind of commercial FA tablet was analyzed using the DPSV technique and HMSM-CTAB-supported organogel electrode.…”

Recent developments in electrochemistry at the interface between two immiscible electrolyte solutions for ion sensing

“…Different fabrication strategies to prepare these µITIES exist and have been reviewed elsewhere. 20,22 ITIES of microscopic dimensions are now routinely used under the form of a single µITIES [43][44][45][46][47][48]37,[49][50][51] ( Figure 1D) or of an array of µITIES [52][53][54][55][56][57][58][59][60][61][62][63][64][65][66][67][68][69][70] ( Figure 1E) allowing to reach limits of detection in the range of tens of nM with an analysis time of a couple of minutes. Diffusion of ionic species at µITIES has shown an asymmetric profile.…”

“…31,32,86 This experimental set-up could be used for the calibration-free determination of ion Target analytes. The sensing of molecules of biological interest (small organic molecules, 52,53,28,87 carbohydrates, 88,29 and proteins 26,[54][55][56]30,[57][58][59][60] ), synthetic organic molecules (drug molecules, 61,43,[62][63][64]81,89 pollutants 44,45,27,42 ) and inorganic species (both cations 36,46,31,32,47,48,33,37,38,49,65,34,39,40,51,50,66,41 and anions 67,35,68 ) has been extensively studied in the 2010-2015 period covered in thi...…”

“…20,22 ITIES of microscopic dimensions are now routinely used under the form of a single µITIES 37,[43][44][45][46][47][48][49][50][51] (Fig. 1D) or of an array of µITIES [52][53][54][55][56][57][58][59][60][61][62][63][64][65][66][67][68][69][70] (Fig. 1E) allowing to reach limits of detection in the range of tens of nM with an analysis time of a couple of minutes.…”

“…The sensing of molecules of biological interest (small organic molecules, 28,52,53,87 carbohydrates, 29,88 and proteins 26,30,[54][55][56][57][58][59][60] ), synthetic organic molecules (drug molecules, 43,61-64,81,89 pollutants 27,42,44,45 ) and inorganic species (both cations [31][32][33][34][36][37][38][39][40][41][46][47][48][49][50][51]65,66 and anions 35,67,68 ) has been extensively studied in the 2010-2015 period covered in this mini-review (see Table 1 of the ESI † for more details). Although the detection of some analytes was already targeted before 2010 (e.g.…”