Electrochemical evaluation and voltammetric determination of laxative drug bisacodyl on boron-doped diamond electrode

Falone, Max Fabrício; Salamanca-Neto, Carlos Alberto Rossi; Moraes, Jaqueline Tobias; Sartori, Elen Romão

doi:10.1016/j.measurement.2019.01.061

Cited by 15 publications

(3 citation statements)

References 29 publications

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“…Electroanalytical techniques are selective, rapid, sensitive and easy methods; they also have low detection and determination limits. So, they have been widely used to analyze organic molecules as pharmaceuticals and pesticides in food, environmental or biological samples and commercial formulations [16][17][18][19][20]. Carbon electrodes, which have great advantages, such as low cost, lightness, large specific surface area, light weight, oxidation resistance, high corrosion resistance and extraordinary porous structure, have a dominant position in the analysis of drugs, pesticides and numerous organic molecules [21].…”

Section: Introductionmentioning

confidence: 99%

Development of a New Analytical Method for Determination of Veterinary Drug Oxyclozanide by Electrochemical Sensor and Its Application to Pharmaceutical Formulation

Demir

Silah

2020

Chemosensors

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A novel highly selective, sensitive and simple analytical technique was recommended for the investigation of anthelmintic veterinary drug oxyclozanide based on square wave anodic stripping voltammetry (SWASV) by using a carbon paste electrode (CPE). According to the cyclic voltammetric data, the oxidation and electron transfer processes of oxyclozanide were found as irreversible and adsorption-controlled, respectively. The voltammetric anodic peak response was characterized with respect to pH, accumulation potential, accumulation time, frequency and pulse amplitude, etc. Under these optimized experimental conditions, the anodic peak density of oxyclozanide was linear to oxyclozanide concentrations in the range from 0.058 to 4.00 mg/L. The described electrochemical method was successfully carried out for the oxyclozanide in pharmaceutical formulation and tap water with mean percentage recovery of 101.5 % and 102.2 %, respectively. The results of pharmaceutical formulation studies were statistically compared to the high-performance liquid chromatographic method.

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Section: Introductionmentioning

confidence: 99%

Development of a New Analytical Method for Determination of Veterinary Drug Oxyclozanide by Electrochemical Sensor and Its Application to Pharmaceutical Formulation

Demir

Silah

2020

Chemosensors

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“…Electrochemical biosensor arrays employing different materials and configurations and allowing chemical functionalization for different applications have been studied [ 22 , 23 , 24 , 25 , 26 ]. Also, diamond-doped electrodes as electrochemical sensors have been used for applications such as water treatment and the development of biosensors [ 27 , 28 ].…”

Section: Introductionmentioning

confidence: 99%

XMEA: A New Hybrid Diamond Multielectrode Array for the In Situ Assessment of the Radiation Dose Enhancement by Nanoparticles

Nicolucci,

Gambaro,

Araujo Silva

et al. 2024

Sensors

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This work presents a novel multielectrode array (MEA) to quantitatively assess the dose enhancement factor (DEF) produced in a medium by embedded nanoparticles. The MEA has 16 nanocrystalline diamond electrodes (in a cell-culture well), and a single-crystal diamond divided into four quadrants for X-ray dosimetry. DEF was assessed in water solutions with up to a 1000 µg/mL concentration of silver, platinum, and gold nanoparticles. The X-ray detectors showed a linear response to radiation dose (r2 ≥ 0.9999). Overall, platinum and gold nanoparticles produced a dose enhancement in the medium (maximum of 1.9 and 3.1, respectively), while silver nanoparticles produced a shielding effect (maximum of 37%), lowering the dose in the medium. This work shows that the novel MEA can be a useful tool in the quantitative assessment of radiation dose enhancement due to nanoparticles. Together with its suitability for cells’ exocytosis studies, it proves to be a highly versatile device for several applications.

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“…The application of electrochemical techniques in the analysis of drugs and pharmaceutical products either in biological medium has increased considerably in recent years (Table 1). [33–68] The renewed interest in electrochemical techniques can be attributed in part to more sophisticated instrumentation and increased understanding of the technique themselves. The application of different electrochemical modes in the analysis of drugs and pharmaceuticals are available for the quantification of drugs.…”

Section: Introductionmentioning

confidence: 99%

Current Trends in Analytical Methods for the Determination of Hydroxychloroquine and Its Application as Treatment for COVID‐19

et al. 2020

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Hydroxychloroquine (HCQ) is a drug indicated in rheumatology for the treatment of rheumatoid arthritis and systemic lupus erythematosus for its anti‐inflammatory and immunomodulatory properties. Many countries such as Morocco have recommended the use of HCQ for the treatment of COVID‐19 infection. This medication is responsible for severe acute poisoning. Therefore, Hospital laboratories have a fundamental role in affirming the diagnosis and assessing the severity of intoxication by measuring HCQ, carried out in the urine and preferably in whole blood. The analytical techniques used are essentially chromatographic. Unfortunately, these reference methods for forensic analyzes are difficult to adapt to emergency due to their delay in reporting results.

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Electrochemical evaluation and voltammetric determination of laxative drug bisacodyl on boron-doped diamond electrode

Cited by 15 publications

References 29 publications

Development of a New Analytical Method for Determination of Veterinary Drug Oxyclozanide by Electrochemical Sensor and Its Application to Pharmaceutical Formulation

Development of a New Analytical Method for Determination of Veterinary Drug Oxyclozanide by Electrochemical Sensor and Its Application to Pharmaceutical Formulation

XMEA: A New Hybrid Diamond Multielectrode Array for the In Situ Assessment of the Radiation Dose Enhancement by Nanoparticles

Current Trends in Analytical Methods for the Determination of Hydroxychloroquine and Its Application as Treatment for COVID‐19

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