Electrochemical Biosensor Based on TiO 2 Nanomaterials for Cancer Diagnostics

Mavrič, Tina; Benčina, Metka; Imani, Roghayeh; Junkar, Ita; Valant, Matjaž; Kralj‐Iglič, Veronika; Iglič, Aleš

doi:10.1016/bs.abl.2017.12.003

Cited by 32 publications

(29 citation statements)

References 154 publications

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“…To prepare biosensors, different types of transducers can be implemented to convert the biorecognition event into a measurable signal as electrochemical, optical or other physical variables [1][2][3][4][5][6]. Electrochemical transducers are widely used in biosensor devices due to the diversity of experimental electrochemical setups, simple data collection and robust interpretation.…”

Section: Introductionmentioning

confidence: 99%

Nanostructured Titanium Dioxide Surfaces for Electrochemical Biosensing

Bertel

Miranda

García-Martín

2021

Sensors

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TiO2 electrochemical biosensors represent an option for biomolecules recognition associated with diseases, food or environmental contaminants, drug interactions and related topics. The relevance of TiO2 biosensors is due to the high selectivity and sensitivity that can be achieved. The development of electrochemical biosensors based on nanostructured TiO2 surfaces requires knowing the signal extracted from them and its relationship with the properties of the transducer, such as the crystalline phase, the roughness and the morphology of the TiO2 nanostructures. Using relevant literature published in the last decade, an overview of TiO2 based biosensors is here provided. First, the principal fabrication methods of nanostructured TiO2 surfaces are presented and their properties are briefly described. Secondly, the different detection techniques and representative examples of their applications are provided. Finally, the functionalization strategies with biomolecules are discussed. This work could contribute as a reference for the design of electrochemical biosensors based on nanostructured TiO2 surfaces, considering the detection technique and the experimental electrochemical conditions needed for a specific analyte.

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Section: Introductionmentioning

confidence: 99%

Nanostructured Titanium Dioxide Surfaces for Electrochemical Biosensing

Bertel

Miranda

García-Martín

2021

Sensors

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“…[27] Researchers have proved the ability of TiO 2 material in biosensor applications. [28,29] In fact, the performance of a biosensor was enhanced by using TiO 2 at nanoscale to implement a sensing mechanism. It is well known that the ability of nanoscale materials is to amplify the electrical response due to smooth electrons transfer rate in the nanostructure medium.…”

Section: Role Of Tio 2 Nanomaterials In Biosensormentioning

confidence: 99%

State-of-the-Art on Functional Titanium Dioxide-Integrated Nano-Hybrids in Electrical Biosensors

Nadzirah

Gopinath

Parmin

et al. 2020

Critical Reviews in Analytical Chemistry

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Biosensors operating based on electrical methods are being accelerated toward rapid and efficient detection that improve the performance of the device. Continuous study in nano-and material-sciences has led to the inflection with properties of nanomaterials that fit the trend parallel to the biosensor evolution. Advancements in technology that focuses on nano-hybrid are being used to develop biosensors with better detection strategies. In this sense, titanium dioxide (TiO 2) nanomaterials have attracted extensive interest in the construction of electrical biosensors. The formation of TiO 2 nano-hybrid as an electrical transducing material has revealed good results with high performance. The modification of the sensing portion with a combination (nano-hybrid form) of nanomaterials has produced excellent sensors in terms of stability, reproducibility, and enhanced sensitivity. This review highlights recent research advancements with functional TiO 2 nano-hybrid materials, and their victorious story in the construction of electrical biosensors are discussed. Future research directions with commercialization of these devices and their extensive utilizations are also discussed.

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“…In the future it will be important to develop novel diagnostic methods based on nanotechnology to quantitatively determine the amount of lilliput particles in the human body. Candidates for reliable and simple sensors of lilliput particles in biofluids are Titanium and Titanium Dioxide (TiO2) nanostructured surfaces which bind lilliput particles [283][284][285][286][287] . Figure 2 shows EV isolate from blood on TiO2 nanotubular surface.…”

Section: Interactions Of Lilliput Particles With New Materialsmentioning

confidence: 99%

From Extracellular Vesicles to Global Environment: A Cosmopolite SARS-Cov-2 Virus<strong> </strong>

Kralj-Iglič¹,

Dahmane²,

T³

et al. 2020

Preprint

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Within the micro and nano world, tiny membrane-enclosed bits of material are more or less free to move and act as communication tools within cells, between cells, between different tissues and between organisms in global environment. Based on the mechanism of membrane budding and vesiculation that includes all types of cells, in this review, we attempted to present a review on SARS-CoV-2 virus actions in compartments of different scales (cells and their surroundings, tissues, organisms and society). Interactions of the virus with cells on a molecular level, with neural system, endothelium, hematopoietic system, gastrointestinal system and genitourinary system. Transmission route between organisms and between mother and fetus are considered. Also, transmission of virus through contact with materials and with environment, the suggested measures to prevent contamination with the virus and to support the organism against the disease are given.

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Electrochemical Biosensor Based on TiO 2 Nanomaterials for Cancer Diagnostics

Cited by 32 publications

References 154 publications

Nanostructured Titanium Dioxide Surfaces for Electrochemical Biosensing

Nanostructured Titanium Dioxide Surfaces for Electrochemical Biosensing

State-of-the-Art on Functional Titanium Dioxide-Integrated Nano-Hybrids in Electrical Biosensors

From Extracellular Vesicles to Global Environment: A Cosmopolite SARS-Cov-2 Virus<strong> </strong>

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