Electroacupuncture to Improve Endometrial Receptivity and Folliculogenesis in Polycystic Ovary Syndrome

Budihastuti, Uki Retno; Melinawati, Eriana; Anggraini, Nutria Widya Purnama; Anggraeni, Asih; Yuliantara, Eric Edwin; Sulistyowati, Sri; Hadi, Cahyono; Nurwati, Ida; Yulyanti,; Octavia, Dhamayanti Eka; Wesliaprilius, Todung Antony; Murti, Bhisma

doi:10.1089/acu.2020.1503

Cited by 2 publications

(2 citation statements)

References 30 publications

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“…A similar study demonstrated that EA improved abnormal follicular development in PCOS patients by inhibiting the overexpression of AMH and increasing the expression of P450arom ( 66 ). The protective effect of EA on follicle growth in patients with PCOS was further confirmed by another clinical study ( 53 , 60 ). In addition, acupuncture at an early stage of oocyte recruitment improved embryo quality in PCOS patients undergoing in vitro fertilization ( 39 ).…”

Section: Potential Mechanisms Of Acupuncture Affecting Pcos-related S...mentioning

confidence: 54%

Underlying mechanisms of acupuncture therapy on polycystic ovary syndrome: Evidences from animal and clinical studies

Yang

Zhou²,

Hu³

et al. 2022

Front. Endocrinol.

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Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder among women of reproductive age. Current standard treatment includes lifestyle change, oral pharmacological agents, and surgical modalities. However, the efficacy of current therapies is less than satisfactory. Clinical evidence has shown that acupuncture is effective for regulating hormone levels, promoting ovulation, and attenuating insulin resistance in patients with PCOS. Acupuncture may affect the production of β‐endorphin, which may lead to gonadotropin-releasing hormone secretion and then affect ovulation, menstrual cycle, and fertility. The mechanism of acupuncture for patients with PCOS has not been comprehensively reviewed so far. Better understanding of the mechanisms of acupuncture would help popularize the use of acupuncture therapy for patients with PCOS. In this narrative review, we aimed to overview the potential mechanisms and evidence-based data of acupuncture on PCOS, and analyze the most frequently used acupoints based on animal and clinical studies. The results of this study will contribute to a better understanding of the current situation in this field.

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Section: Potential Mechanisms Of Acupuncture Affecting Pcos-related S...mentioning

confidence: 54%

Underlying mechanisms of acupuncture therapy on polycystic ovary syndrome: Evidences from animal and clinical studies

Yang

Zhou²,

Hu³

et al. 2022

Front. Endocrinol.

View full text Add to dashboard Cite

show abstract

“…Li [72] found that EA combined with CHM not only improved the PR in PCOS patients (82.5% vs. 60% P < 0.05), but also reduced the incidence of adverse effects such as LUFS and OHSS during ovulatory treatment (2.5% vs. 20%,0% vs. 15.0% P < 0.05). Budihastuti et al [73] draw a similar conclusion that LET combined with EA in ovulation induction therapy for PCOS patients could significantly improve uterine hemodynamics, promote follicle development (19.86 ± 0.7 mm vs. 13.92 ± 3.61 mm P < 0.05), and increased endometrial thickness (8.22 ± 1.76 mm vs. 6.95 ± 1.82 mm P < 0.05) [73]. In addition, Peng et al [74] found that EA improved DAEA-induced IR, mitochondrial dysfunction, and endoplasmic reticulum stress in a rat model of PCOS by inhibiting the mTOR/4E-BP1 signaling pathway, and reversed the beneficial effects of EA on PCOSlike rats by inhibiting autophagy in a reversion experiment in which rats with improved symptoms were injected with 3-MA (autophagy inhibitor).…”

Section: Clinical Efficacy Of Acupuncture In the Treatment Of Pcosmentioning

confidence: 99%

The Application of Complementary and Alternative Medicine in Polycystic Ovary Syndrome Infertility

Shi

Wang

Zhu

et al. 2022

Evidence-Based Complementary and Alternative Medicine

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Polycystic ovary syndrome (PCOS) is a lifelong reproductive endocrine disease, which is the most common cause of anovular infertility. Modern medicine mainly treats infertile patients with PCOS by improving living habits, ovulation induction therapy, and assisted reproductive technology (ART), but the effect is not satisfied. Complementary alternative medicine (CAM) has conspicuous advantages in the treatment of PCOS infertility due to its good clinical efficacy, wide mechanism of action, and no obvious adverse reactions, but its safety and effectiveness in the treatment of PCOS infertility have not been proved. Based on the existing clinical and experimental studies, this paper looks for the therapeutic effect and the mechanism behind it, and explores the safety and effectiveness of its treatment in PCOS infertility, in order to provide reference for future clinical treatment and experimental research.

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Electroacupuncture to Improve Endometrial Receptivity and Folliculogenesis in Polycystic Ovary Syndrome

Cited by 2 publications

References 30 publications

Underlying mechanisms of acupuncture therapy on polycystic ovary syndrome: Evidences from animal and clinical studies

Underlying mechanisms of acupuncture therapy on polycystic ovary syndrome: Evidences from animal and clinical studies

The Application of Complementary and Alternative Medicine in Polycystic Ovary Syndrome Infertility

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