Ekspresi Interleukin-1 (Il-1) Β Pada Endometriosis, Karsinoma Endometrioid Dan Karsinoma Serosum Ovarium

Abstract

ABSTRAK Kata kunci: Endometriosis, interleukin-1β, karsinoma endometrioid, karsinoma serosum ABSTRACT Ovarian endometriosis is associated with an increased risk of ovarian epithelial carcinoma (RR 1.9-4.2). Endometrioid carcinoma is one of the most common type of malignancy associated with endometriosis, while serous carcinoma is the most common ovarian cancer type. It has been reported that sera pro-inflammatory interleukin-1 (IL-1) β evidently be involved in both endometriosis (p = 0,034 and p=0,020), while group B vs group C was not significant (p = 0,805). There are some differences in IL-1β expression among ovarian endometriosis, endometrioid carcinoma, and serosum carcinoma, but there are no significantly difference between ovarian endometrioid carcinoma and serosum carcinoma.