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Abstract

Chitin is the second most important natural amino polysaccharide polymer after cellulose in the world. The main sources exploited are marine crustaceans, shrimp, and crab apart from that some other lobstera, insects, sulphur butter and fungi. Chitosan is the most important natural based common cationic polymer got from chitin has gotten developing consideration for the most part due to their biodegradable , biocompatible, bio-renewable and non-lethal properties. The deacetylated chitin derivative chitosan is a useful and interesting bioactive polymer; it has a large pharmaceutical application either. It has numerous reactive amino side groups, which offer possibilities of chemical modifications, formation of a large variety of beneficial derivatives. Chitosan has been found to be used as a support material for pharmaceutical application, gene delivery, cell culture, and tissue engineering. This review is based on the various pharmacological activity of chitosan such as wound healing, anti-hypertensive, anti-cancer, blood coagulant, anti-coagulant, anti-ulcer, anti-microbial, anti-viral, hypolipidemic and hypocholesterolemic etc.

Polysaccharide-Based Transdermal Drug Delivery

“…Polymeric films have attracted interest as an alternative to patches because they are transparent, flexible, non-occlusive, and easy to administer while prolonging the drug retention time in the skin [ 79 ]. The films demonstrate greater drug loading and better drug release than ointment [ 80 ].…”

Edible insects: non-food and non-feed industrial applications

“…Chitin and chitosan, the deacetylated derivative of chitin, have a widespread application in nutrition and biomedicine. They exert anti-cancer, antioxidant and antimicrobial functions, and can also be used for tissue engineering, biomedicine, wound healing processes, microencapsulation and sustained drug delivery applications (Jacob et al, 2020;Tripathi and Singh, 2018). Chitinases are employed in antifungal creams and lotions, while chitin derivatives have a number of applications such as in the making of contact lenses, artificial skin, and surgical stitches (Singh et al, 2022).…”

Chitosan nanoparticles improve the effectivity of miltefosine against Acanthamoeba

“…It is produced through the N-deacetylation of chitin and exhibits similarities to cellulose [ 17 ]. Chitosan has various pharmacological properties such as immune-potentiation, antioxidant, and antibacterial activities [ 18 ]. Chitosan nanoparticles (CS-NPs) have been employed as a drug delivery system to treat Plasmodium vivax and Leishmania [ 19 , 20 ].…”