Einfache methode zur trennung und quantitativen bestimmung von Kawa-Laktonen durch hochleistungs-flüssigkeits-chromatographie

HPLC analysis of flavokavins and kavapyrones from Piper methysticum Forst.

“…For a good and rapid separation of crude drug extracts silica gel columns were used [17]. Furthermore, RP materials were taken for analysis [18].…”

Analysis of plant extracts by NIRS: simultaneous determination of kavapyrones and water in dry extracts of Piper methysticum Forst.

“…The kavapyrones (methysticin, dihydromethysticin, kavain, dihydrokavain, yangonin and desmethoxyyangonin) are known to be the active substances and are therefore used for standardisation. Several HPLC methods for the determination and quantification of these six major components have been published [12][13][14][15].…”

Analysis of kavalactones from Piper methysticum (kava-kava)

“…The first paper concerning HPLC analysis of kavakava extracts and preparations was published in 1980 by Gracza and Ruff [32]. The analysis was carried out using a Nucleosil 100-5 column eluting with a binary system nhexane-dioxane (85:15).…”

“…The eluent system was very similar to that reported by Gracza and Ruff [32]. Detection was carried out at 250 nm, using 3,4-dimethoxybenzaldeyde as internal standard.…”