Ein Beitrag zum Problem der sogenannten Pyodermia ulcerosa

Two Cases of Pyoderma (Ecthyma) Gangraenosum Associated with the Presence of an Abnormal Serumprotein (β₂A-paraprotein)

“…In a num ber of cases, changes ranging from swelling of the intim a to thrombosis and necrosis have been found in arterioles and venules [48,73,45,67,57,69,39,62]. Other authors did not find any changes in the blood ves sels [39,55,8,33,25,36].…”

“…Becke and Rose (1959) [3], Kresbach (1959) [36] and most recent authors reject the hypothesis of infection. The first two authors write: " The organisms usually reported in this disease could be expected to exhibit some sensitivity to the wide variety of antibiotics used and the lack of response in this case to such agents is notable.…”

“…pyocyaneus w ithout effecting healing. Kresbach (1959) [36] thinks th at this last patient had pyoderma gangraenosum.…”

“…The last group, of 54 patients, had no intestinal disorders [22,66,37,18,51,19,23,46,21,72,44,35,33,25,47,74,67,43,65,55,1,53,58,28,5,36,50,57,69,63,41,31,62,29], I. (a) The association o f pyoderma gangraenosum and arthritis in the patients with colitis ulcerosa.…”

Pyoderma gangraenosum mit Philadelphia-Chromosom-negativer chronischer myeloischer Leukämie

“…Die anfangs bestehenden roten Flecken oder lividen Knötchen exulzerieren bald. Die so entstehenden Ulzera sind von einem livid-roten Randsaum umgeben und nehmen rasch an Grösse zu [3,18].…”