Pyoderma gangraenosum mit Philadelphia-Chromosom-negativer chronischer myeloischer Leukämie

Kövary, Peter Michael; Lonauer, G; Niedorf, H. R.; Nautsch, C; Pawlowitzki, I. H.

doi:10.1159/000251095

Cited by 6 publications

(1 citation statement)

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“…The frequency of occurrence of malignant neoplasms in the cases of pyoderma gangrenousm is not exactly determined, but it can be assessed to be at 7% 10 . In these cases the most often is association with acute 11–13 or chronic leukaemia 14,15 as well as in children and in adult groups. Bullous type of pyoderma gangrenosum is a typical coexistence for leukaemia 12,13 .…”

Section: Discussionmentioning

confidence: 99%

Pyoderma gangrenosum coexisting with acute myelogenous leukaemia

Krauze¹,

Brzeźińska-Wcisło²,

Kamińska‐Winciorek³

et al. 2005

Acad Dermatol Venereol

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The frequency of occurrence of malignant neoplasms in the cases of pyoderma gangrenosum is not exactly determined, but it can be assessed to be at 7%. The aim of the study was to report a 26-year-old male patient with pyoderma gangrenosum coexisting with acute myelogenous leukaemia. The first skin lesions on both tibia occurred in June 2001. Prior to the proper diagnosis of pyoderma gangrenosum, the patient was treated surgically. Because of the dramatic dermatological and general condition in November 2001, the patient was admitted to the Dermatological Department of the Silesian Medical Academy in Katowice where the diagnosis of pyoderma gangrenosum was established. On the clinical and biochemical picture, the diagnosis of pyoderma gangrenosum within acute myelogenous leukaemia was made. Initially, cyclosporin A 200 mg orally per day in the therapy of pyoderma gangrenosum was administered to achieve a slight clinical improvement. Although chemotherapy leukaemia was performed, the patient died after 4 months of the confirmation of the acute myelogenous leukaemia diagnosis.

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