Eight-year multimodal follow-up of recurrent idiopathic acute exudative polymorphous vitelliform maculopathy

Astakhov, Yuriy Sergeyevich; Astakhov, Sergey Yu.; Lisochkina, Alla B.; Nechiporenko, P. A.

doi:10.1016/j.jfo.2020.01.004

Cited by 1 publication

(2 citation statements)

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“…[2][3][4] There is little information on the natural course and treatment options. 5 Recurrence of AEPVM is rare and only 1 previous case of recurrent AEPVM has been published. 5 We describe a case of AEPVM that recurred 9 years after the initial event.…”

Section: Introductionmentioning

confidence: 99%

“…5 Recurrence of AEPVM is rare and only 1 previous case of recurrent AEPVM has been published. 5 We describe a case of AEPVM that recurred 9 years after the initial event. The patient was treated successfully with oral prednisolone followed by intravitreal dexamethasone implant, and was monitored with international standard pattern and full-field electroretinogram (PERG; ERG) and electro-oculogram (EOG) testing.…”

Section: Introductionmentioning

confidence: 99%

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A case of recurring acute exudative polymorphous vitelliform maculopathy successfully treated with intravitreal Ozurdex injection

Lodhia

Robson

Khoda

et al. 2023

European Journal of Ophthalmology

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Introduction We describe a case of acute exudative polymorphous vitelliform maculopathy (AEPVM) that recurred 9 years after the initial event. To the best of our knowledge, this is the first report of recurrent AEPVM showing recovery of retinal and retinal pigment epithelium (RPE) function and good visual outcome following treatment with intravitreal corticosteroid. Case description A 45-year-old Caucasian woman first presented with AEVPM in 2009. Her condition spontaneously resolved and she remained stable over several years. 9 years later, her condition recurred with bilateral reduction in visual acuity. Fundus examination revealed multiple small yellowish subretinal lesions across the posterior pole in both eyes. Optical coherence tomography (OCT) showed bilateral cystoid macular oedema (CMO). She was referred for electrophysiology and her electrooculogram findings were in keeping with severe generalised RPE dysfunction bilaterally, with a light peak to dark trough ratio (Arden index) of 110%, comparable to her initial presentation 9 years earlier. She was initially treated with oral steroids with some improvement. However, the maculopathy in the left eye recurred on cessation of oral treatment. A sustained-release 700ug dexamethasone intravitreal implant (Ozurdex®) was inserted in the left eye to which she responded remarkably, with improvement in visual acuity and complete resolution of the CMO. A year later, at her most recent clinic visit in March 2021, there was no evidence of any further recurrence. Conclusion Our case demonstrates clinical and imaging findings consistent with recurrence of AEPVM with CMO that has been successfully treated with Ozurdex®.

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