Efficacy of Acellular Dermal Matrix and Coronally Advanced Flaps for the Treatment of Induced Gingival Recession Defects: A Histomorphometric Study in Dogs

Abstract

ADM might yield similar results to a CAF alone and could decrease the amount of KG.

Biodegradable gelatin/beta‐tricalcium phosphate sponges incorporating recombinant human fibroblast growth factor‐2 for treatment of recession‐type defects: A split‐mouth study in dogs

“…Previous studies employing similar canine models have demonstrated that the coronally advanced flap with or without CTG healed with a long junctional epithelium and limited bone and cementum regeneration; the mean height of periodontal regeneration was <1 mm. These results were confirmed by human histological studies wherein no periodontal regeneration was evident at 9 months . Thus, our observations suggest that a gelatin/β‐TCP sponge may be used safely with rhFGF‐2 as an adjunct to the coronally advanced flap in support of periodontal regeneration in gingival recession defects.…”

“…Full mouth scaling was performed using an ultrasonic scaler. Artificial recession‐type defects were surgically created on the buccal surfaces of maxillary canine teeth according to a protocol by Al‐Hezaimi et al., with modifications . A semicircular incision to remove keratinized gingival tissue was made using a no.…”

Efficacy of acellular dermal matrix and autogenous connective tissue grafts in the treatment of gingival recession defects among Asians

“…The present clinical results showed no significant differences in the efficacy of ADM and sCTG in the treatment of GR defects. Our results are in accordance with a recent experimental investigation . Placement of sCTG under a coronally‐repositioned flap allows the connective tissue of the palatal masticatory mucosa to induce differentiation of the epithelial cells of the thin covering flap into a keratinizing cell .…”

“…An explanation in this regard could be derived from the fact that collagen fibers present in the ADM membrane facilitate root coverage by stimulating platelet attachment, enhancing fibrin linkage, and having a chemotactic effect on nearby fibroblasts . However, controversial results have also been reported . Other advantages that suggest ADM as a substitute to FGG include elimination of donor site morbidity and reduction in postoperative discomfort and complications …”

“…13 However, controversial results have also been reported. 14 Other advantages that suggest ADM as a substitute to FGG include elimination of donor site morbidity and reduction in postoperative discomfort and complications. 15,16 To our knowledge, from indexed literature, a limited number of studies have compared the clinical efficacy of ADM with sCTG in the treatment of GR defects; however, the results remain debatable.…”