Efficacy of a single dose of low-level laser therapy in reducing pain, swelling, and trismus following third molar extraction surgery

Landucci, Alex; Wosny, A.C.; Uetanabaro, Lucas Caetano; Moro, Alexandre; Araújo, Maria Christina Barbosa de

doi:10.1016/j.ijom.2015.10.023

Cited by 82 publications

(57 citation statements)

References 22 publications

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“…Actually, the removal of the third molar is a very common procedure and the secondary effects are swelling, pain and trismus. In a study to evaluate two anti-inflammatory drugs (ibuprofen and/or dexamethasone) in third-molar surgery, no statistically significant advantage was found between treatments, suggesting that ibuprofen could be used as a single antiinflammatory drug in the management of this procedure [12,28]. In recent studies, submucosal dexamethasone has been used as treatment to control postoperative discomfort, showing a significant reduction of pain, swelling and truisms compared with NSAIDs [29].…”

Section: Resultsmentioning

confidence: 99%

Clinical trial evaluating the effectiveness of biocompound IMMUNEPOTENT CRP in the third-molar extraction

Franco‐Molina

Mendoza‐Gamboa

Coronado‐Cerda

et al. 2016

Biotechnology & Biotechnological Equipment

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A controlled, parallel, randomized and comparative trial was carried out to evaluate the antiinflammatory efficacy of IMMUNEPOTENT CRP versus ibuprofen in patients after third-molar surgery over seven days. The anti-inflammatory efficacy of IMMUNEPOTENT CRP was evaluated using the method of Amin and Laskin, and the analysis of cytokine production (IL-2, IL-4, IL-6, IL-10, TNF-a, INF-g) in saliva was done by flow cytometry. The swelling process after surgery was significant (p < 0.05) and the treatments with IMMUNEPOTENT CRP or ibuprofen controlled this process properly; no difference between the groups was found (p < 0.05). Both treatments were shown to modulate the cytokine production. These results demonstrate the anti-inflammatory activity of the natural compound IMMUNEPOTENT CRP and suggest it could be used in clinical dental practice.

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Section: Resultsmentioning

confidence: 99%

Clinical trial evaluating the effectiveness of biocompound IMMUNEPOTENT CRP in the third-molar extraction

Franco‐Molina

Mendoza‐Gamboa

Coronado‐Cerda

et al. 2016

Biotechnology & Biotechnological Equipment

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“…20 Over the last few years, a number of studies demonstrat- ed the positive effects of low-level laser therapy (LLLT) on reduction of postoperative discomfort. 10,12 Ozturan et al used Neodymium-Doped Yttrium Aluminium Garnet (Nd:YAG) laser (1064 nm, 0.5 W, 8 J/cm 2 , and 60 seconds, immediately after surgery) for LLLT after maxillary sinus lift procedure. They found that swelling and the oral health-related quality of life was significantly improved in the LLLT group compared to the control group.…”

Section: Discussionmentioning

confidence: 99%

“…However, most of these techniques did not show beneficial effects. [8][9][10][11][12] Although administration of corticosteroids to control postoperative sequelae is popular, 13 there are serious concerns about their adverse impacts. The most potential side effects of corticosteroids are adrenal suppression, osteonecrosis, impaired wound healing, and increased risk of postoperative infection.…”

Section: Introductionmentioning

confidence: 99%

Periosteal Releasing Incision With Diode Laser in Guided Bone Regeneration Procedure: A Case Series

et al. 2016

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Introduction: Periosteal releasing incision (PRI) is nearly always essential to advance the flap sufficiently for a tension-free flap closure in bone augmentation procedures. However, hematoma, swelling, and pain are recognized as the main consequences of PRI with scalpel. The aim of this case series was to investigate the effectiveness of laser-assisted PRI in guided bone regeneration (GBR) procedure. In addition, postoperative hematoma, swelling, and pain and implant success were assessed. Methods: Seventeen patients needed GBR were included in this study. Diode laser (940 nm, 2 W, pulse interval: 1 ms, pulse length: 1 ms, contact mode, 400-μm fiber tip) was used in a contact mode to cut the periosteum to create a tension-free flap. Facial hematoma, swelling, pain, and the number of consumed nonsteroidal anti-inflammatory drugs (NSAIDs) were measured for the six postoperative days. Six months after implant loading, implant success was evaluated. Results: Minimal bleeding was encountered during the procedure. A tension-free primary closure of the flap was achieved in all cases. The clinical healing of the surgical area was uneventful. None of the patients experienced hematoma, ecchymosis, or intense swelling after surgery. The mean value of maximum pain (visual analogue scale -VAS) was 20.59 ± 12.10 mm (mild pain). Patients did not need to use NSAID after four postoperative days. All implants were successful and functional and none of them failed after 6 months of implant loading. Conclusion: This study revealed the effectiveness of laser-assisted PRI in GBR procedure. This technique was accompanied with minimal sequelae at the first postoperative week. All implants were successful and no complication was noted during the course of this study.

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“…It uses a lowintensity Laser to provide a potential treatment. This approach has been used to treat hair loss, rheumatic problems, pain relief, and enhance muscle strength [97,98]. Like other modalities, the LA has advantages and limitations in some applications.…”

Section: Laser Ablationmentioning

confidence: 99%

Thermal Therapy Modalities for Cancer Treatment: A Review and Future Perspectives

Mellal¹,

Oukaira²,

Kengene³

et al. 2017

Appl Sci Res Rev

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Efficacy of a single dose of low-level laser therapy in reducing pain, swelling, and trismus following third molar extraction surgery

Cited by 82 publications

References 22 publications

Clinical trial evaluating the effectiveness of biocompound IMMUNEPOTENT CRP in the third-molar extraction

Clinical trial evaluating the effectiveness of biocompound IMMUNEPOTENT CRP in the third-molar extraction

Periosteal Releasing Incision With Diode Laser in Guided Bone Regeneration Procedure: A Case Series

Thermal Therapy Modalities for Cancer Treatment: A Review and Future Perspectives

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