2008
DOI: 10.1097/yic.0b013e32830c202d
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Effects of venlafaxine extended release on resilience in posttraumatic stress disorder: an item analysis of the Connor–Davidson Resilience Scale

Abstract: The aim was to evaluate the efficacy of venlafaxine extended release (ER) on characteristics of resilience, measured by the Connor-Davidson Resilience Scale, in patients with posttraumatic stress disorder (PTSD). Data were evaluated from a randomized, 6-month, international, multicenter study of adult outpatients with a primary diagnosis of Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition PTSD for >or=6 months, and 17-item Clinician-Administered PTSD Scale score >or=60. Patients were assig… Show more

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Cited by 42 publications
(39 citation statements)
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“…Our data confirm and extend these findings in non-psychiatric patients using CD-RISC-10. We did not find a significant association between past psychiatric diagnoses and resilience levels, suggesting that global resilience scores could be a reversible state-like index of mental health as also suggested by two randomized placebo-controlled trials of antidepressants in Alzheimer's caregivers and PTSD patients [29], [30]. Interestingly, the association was only significant with current anxiety disorders (especially GAD), comorbid with mood disorder or not, but not with mood disorder without anxiety.…”
Section: Discussionmentioning
confidence: 42%
See 1 more Smart Citation
“…Our data confirm and extend these findings in non-psychiatric patients using CD-RISC-10. We did not find a significant association between past psychiatric diagnoses and resilience levels, suggesting that global resilience scores could be a reversible state-like index of mental health as also suggested by two randomized placebo-controlled trials of antidepressants in Alzheimer's caregivers and PTSD patients [29], [30]. Interestingly, the association was only significant with current anxiety disorders (especially GAD), comorbid with mood disorder or not, but not with mood disorder without anxiety.…”
Section: Discussionmentioning
confidence: 42%
“…The fact that CD-RISC scores change in (non-resilient) chronic PTSD patients following pharmacological treatment, suggests that this scale can evaluate resilience but also recovery abilities [28], [30]. Future longitudinal studies in different samples focusing on the effect of trauma exposure on resilience evaluation and growth following adversity are required to explore this question.…”
Section: Discussionmentioning
confidence: 99%
“…When examining multiple risk and protective factors, several modifiable factors emerge. Resilience, social support, and shame can be tackled with targeted interventions including Interpersonal Therapy to address social support, and venlafaxine to increase resilience (Bruce et al, 2004; Davidson et al, 2008). Continued assessment of the differential utility of interventions in the context of postpartum SI is warranted and certain interventions may be more effective at various time points postpartum.…”
Section: Discussionmentioning
confidence: 99%
“…The concept of resilience also has been integrated into clinical practice. A clinical trial with PTSD patients showed a significant association between venlafaxine extended release effect and individual resilience (Davidson et al, 2008). …”
Section: Discussionmentioning
confidence: 99%