Effects of Supplementation with Neptune Krill Oil (Euphasia Superba) on Selected Redox Parameters and Pro-Inflammatory Markers in Athletes during Exhaustive Exercise

Abstract

This study investigated the effects of supplementation with Krill oil on levels of pro-oxidant/antioxidant balance markers and levels of pro-inflammatory cytokines in professional rowers

A 21-day Daniel fast with or without krill oil supplementation improves anthropometric parameters and the cardiometabolic profile in men and women

“…Our findings therefore strongly contradict the work of Bunea et al [8], who reported that krill oil supplementation (1–3 g/day for 90 days) increased HDL-C (43-60%) and decreased LDL-C (32-39%). On the other hand, our findings support the results of recent investigations [9,12,13] that found no effect for krill oil supplementation (2 g/day for 28 days, 1 g/day for 42 days, and 3 g/day for 49 days, respectively) on blood lipids. The baseline LDL-C values in the Bunea et al study (165–183 mg/dL) [8] were considerably larger than the corresponding values of the other investigations mentioned in this paragraph (including the present study) [9,12,13].…”

“…This may explain why only Bunea and colleagues [8] found that krill oil supplementation reduced LDL-C. However, baseline HDL-C concentrations were similar across studies (also including the present study) [8,9,12,13], leaving little scientific explanation for the striking improvement in this cholesterol noted by Bunea et al [8]. Due to the inability of krill oil supplementation to affect any outcome measure in the present study, values for subjects in both the krill oil and placebo conditions were collapsed and are discussed as such from this point forward.…”

Advances in Technologies for Highly Active Omega-3 Fatty Acids from Krill Oil: Clinical Applications

“…An investigation of potential mechanisms of action was then carried out on DLD-1 and HT-29 cell lines treated with FFAE of krill oil at 8 and 24 h. From the evaluation of epidermal growth factor receptor (EGFR) signaling, the results indicated that FFAE of krill oil, at 0.03 and 0.12 µL/100 µL, induced reduction in EGFR, pEGFR, pERK1/2 and pAKT expression without any changes in total ERK1/2 and AKT levels. The expression of the ligand PD-L1 was significantly inhibited by FFAE of krill oil [155].…”

Effects of Krill Oil and Race Distance on Serum Choline and Choline Metabolites in Triathletes: A Field Study

“…Given that prolonged periods of high-intensity long-duration exercise may also negatively impact immune function and inflammation, there is considerable interest in marine-based n-3 PUFA supplementation as a means to improve athletic recovery (8). To this end, studies that have investigated the benefits of krill oil in sports settings to date have focused on post-exercise immune function (9), post-exercise oxidative stress (10), and mTOR signaling (11). However, while krill oil is an acknowledged dietary supplement to provide n-3 PUFAs, no sports nutrition studies have looked at the lesser known aspect of krill oil being a rich source of the essential nutrient choline.…”