Effects of Simultaneous Administration of Estrogen and Parathyroid Extract upon Teeth, Periodontium, and Long Bones of Growing Albino Mice

Abstract

Numerous studies have been carried out concerning the effect of parathyroid extract upon the calcified dental structures and adjacent alveolar bone.1-7 Most of these studies utilized the rat, pigeon, or dog rather than the mouse. This latter animal was employed by Silberberg and Silberberg,8' I but the calcified dental structures and the alveolar process were not evaluated in their studies.In contrast, extensive work has been reported on the effect of estrogens upon the growth of long bones in numerous species of animals. The mouse has been studied probably more extensively than any other animal owing, in part, to the fact that it responds so readily and remarkably to this hormone.'0 However, studies of the effects of estrogens upon tooth structure and associated alveolar bone have not been as extensive or shared the popularity of the corresponding observations upon the long bones."-"' Even less