Effects of microcystins-containing cyanobacteria from a temperate ecosystem on human lymphocytes culture and their potential for adverse human health effects

Mankiewicz-Boczek, Joanna; Palus, Jadwiga; Gągała, Ilona; Izydorczyk, Katarzyna; Jurczak, Tomasz; Dziubałtowska, Elżbieta; Stępnik, Maciej; Arkusz, Joanna; Komorowska, Magdalena; Skowron, Aleksandra; Zalewski, Maciej

doi:10.1016/j.hal.2011.01.001

Cited by 25 publications

(15 citation statements)

References 51 publications

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“…In previous studies, the presence of CYN was revealed in 17 lakes in Poland. The concentrations of the toxin in seston ranged from trace amounts to 3.0 µg dm -3 (Kokociński et al 2009(Kokociński et al , 2013 and were comparable to the concentrations determined in German water bodies during the bloom of Aph. flos-aquae (Preußel et al 2006, Rücker et al 2007).…”

Section: Cyanotoxins In Polish Water Bodiessupporting

confidence: 77%

Cyanobacteria and cyanotoxins in Polish freshwater bodies

Kobos

Błaszczyk

Hohlfeld

et al. 2013

Oceanological and Hydrobiological Studies

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In this work, the authors examined the presence of cyanobacteria and cyanotoxins in 21 samples collected from fresh water bodies located in 5 provinces in Poland: Lublin (2), Podlasie (1), Pomerania (6), Warmia-Masuria (1) and Wielkopolska (11). In addition, to determine the general pattern of geographical distribution, frequency of cyanobacteria occurrence, and cyanotoxins production, the published data from 238 fresh water bodies in Poland were reviewed. On the basis of these collected results, we concluded that Planktothrix, Aphanizomenon, Microcystis and Dolichospermum were dominant. The general pattern in geographical distribution of the identified cyanobacterial genera was typical of other eutrophic waters in Europe. The production of cyanotoxins was revealed in 18 (86%) of the 21 samples analyzed in the present work and in 74 (75%) of the 98 total water bodies for which the presence of toxins had been examined. Among the 24 detected microcystin variants, [Asp 3 ]MC-RR was most common. These results can be verified when more data from the less explored water bodies in the southern and eastern parts of Poland are available.

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Section: Cyanotoxins In Polish Water Bodiessupporting

confidence: 77%

Cyanobacteria and cyanotoxins in Polish freshwater bodies

Kobos

Błaszczyk

Hohlfeld

et al. 2013

Oceanological and Hydrobiological Studies

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show abstract

“…The Antx-a concentration was determined by HPLC using a diode array detection (DAD) detector (model SPD-M20A Prominence HPLC, Shimadzu, USA) according to the method described by Mankiewicz et al [22]. Analysis of the pure extract revealed the presence of Antx-a at a concentration of 2.2 mg/l.…”

Section: Pure Extract Preparations and Analysis Of Anatoxin-amentioning

confidence: 99%

Pro- and anti-inflammatory cytokine expression in carp blood and head kidney leukocytes exposed to cyanotoxin stress – An in vitro study

Rymuszka

Adaszek

2012

Fish & Shellfish Immunology

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“…Cyanobacterial extracts were prepared as in our previous studies (Mankiewicz-Boczek et al, 2011); specifically, 1000 mg of freezedried cyanobacterial material for each sample were dissolved in 60 ml of 75% methanol and sonicated on ice for 10 min to release toxic compounds from cyanobacterial cells. Afterwards, samples were centrifuged for 10 min at 10,000× g at 4 • C. At the end, the supernatants were filtered using Whatman solid-state PTFE filters.…”

Section: Crude Cyanobacterial Extractsmentioning

confidence: 99%

“…Microcystins in crude and purified cyanobacterial extracts were determined as described by Mankiewicz-Boczek et al (2011). Briefly, analysis was performed by HPLC with a diode array detection (DAD) detector (model 1100, Hewlett Packard) according to the method principle of Meriluoto and Codd (2005).…”

Section: Analysis Of Microcystinsmentioning

confidence: 99%