Effects of Intravenous Versus Inhalational Anesthesia on Red Cell Distribution Width and Mean Platelet Volume in Patients Undergoing Coronary Artery Surgery

Abstract

INTRODUCTION: The effects of midazolam-based intravenous anesthesia (TIVA) and sevoflurane-based inhalation anesthesia (SEVO) maintenance on postoperative hematological parameters were compared in patients undergoing coronary artery surgery. METHODS: The 100 patients included in the study were divided into two groups according to the anesthesia management: All patients' anesthesia inductions were performed with 10 μgkg-1 fentanyl, 0.15 mgkg-1 midazolam, and 0.8 mgkg-1 rocuronium. Anesthesia was maintained with total intravenous anesthesia in the TIVA group patients, while sevoflurane was used in the SEVO group patients. Demographic, clinical, operative data, red cell distribution width (RDW), and mean platelet volume (MPV) values were recorded. RESULTS: Except that the extubation time was shorter in the SEVO group, no difference was observed between the groups in terms of all these variables. There was a significant increase in postoperative RDW and MPV measurements in both groups. Postoperative RDW value was lower in the inhalation anesthesia group compared to the TIVA group (p=0.013). DISCUSSION AND CONCLUSION: In our study, RDW was found to be lower in the inhalation anesthesia group, indicating less inflammation. There was no difference in terms of postoperative complications and mortality.

Effects of the Anesthesia Type on Hematological Parameters in Coronary Artery Bypass Grafting

“…They reported that the NLR values at the 12 th and 24 th postoperative hours were lower in propofol anesthesia than in desflurane anesthesia. Özay et al [23] compared the effects of midazolam-based TIVA with those of sevoflurane-based inhalation anesthesia on RDW and MPV in patients who underwent CABG. They reported that RDW values were significantly lower in the inhalation group.…”