Effects of high β-glucan barley on visceral fat obesity in Japanese individuals: A randomized, double-blind study

Aoe, Seiichiro; Ichinose, Yasunori; Kohyama, Noriko; Komae, Kôzô; Takahashi, Asuka; Abe, Daigo; Yoshioka, Terutaka; Yanagisawa, Takashi

doi:10.1016/j.nut.2017.05.002

Cited by 88 publications

(57 citation statements)

References 14 publications

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“…β-Glucan in barley significantly treats obesity that reduced low-density lipoprotein, total cholesterol, and serum p-cresyl sulfate levels and increased flow-mediated dilation [90,91]. Barley β-glucan can prevent visceral fat (≥100 cm 2 ) obesity and increase faecal scores, but decreased nutrient digestibility and antiobesity [92,93]. RS and β-glucans as well as soluble arabinoxylan were utilized mainly in the caecum, especially RS shifted the utilization of other polysaccharides to more distal parts of the colon of pigs [94].…”

Section: Healthy Effects Of Functional Ingredients In Barley Grainsmentioning

confidence: 99%

Molecular Mechanism of Functional Ingredients in Barley to Combat Human Chronic Diseases

Zeng

et al. 2020

Oxidative Medicine and Cellular Longevity

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Barley plays an important role in health and civilization of human migration from Africa to Asia, later to Eurasia. We demonstrated the systematic mechanism of functional ingredients in barley to combat chronic diseases, based on PubMed, CNKI, and ISI Web of Science databases from 2004 to 2020. Barley and its extracts are rich in 30 ingredients to combat more than 20 chronic diseases, which include the 14 similar and 9 different chronic diseases between grains and grass, due to the major molecular mechanism of six functional ingredients of barley grass (GABA, flavonoids, SOD, K-Ca, vitamins, and tryptophan) and grains (β-glucans, polyphenols, arabinoxylan, phytosterols, tocols, and resistant starch). The antioxidant activity of barley grass and grain has the same and different functional components. These results support findings that barley grain and its grass are the best functional food, promoting ancient Babylonian and Egyptian civilizations, and further show the depending functional ingredients for diet from Pliocene hominids in Africa and Neanderthals in Europe to modern humans in the world. This review paper not only reveals the formation and action mechanism of barley diet overcoming human chronic diseases, but also provides scientific basis for the development of health products and drugs for the prevention and treatment of human chronic diseases.

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Section: Healthy Effects Of Functional Ingredients In Barley Grainsmentioning

confidence: 99%

Molecular Mechanism of Functional Ingredients in Barley to Combat Human Chronic Diseases

Zeng

et al. 2020

Oxidative Medicine and Cellular Longevity

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show abstract

“…The intake of high-β-glucan barley (cultivar, Kirarimochi, 2 g of β-glucan per day intake) led to significant and safe reductions in visceral fat area (VFA), body weight, BMI, and waist circumference in obese subjects with VFA ≥100 cm 2 compared with the placebo group (cultivar, bgl, 0 g per day intake). Barley high in β-glucan may help prevent visceral fat obesity [47].…”

Section: Agricultural Products Registered In the Ffcmentioning

confidence: 99%

“…In addition, NARO aimed to build a database of functional agricultural products and create a functional food delivery system that address personal health conditions, establish a nutrition care station, and produce a functional boxed lunch (O-Bento) that contributes to the maintenance and improvement of personal health. As the results of this project, NARO contributed assessments of the health benefits of β-glucan rich barley [47], β-conglycinin rich soybean [48], rutin rich tartary buckwheat [49], quercetin rich onion [50], β-cryptoxanthin lunch can reduce AVF. This study showed that continuous intake of a functional box lunch might decrease visceral fat area [56].…”

Section: Study Of Health-promoting Effects Of Agricultural Products Bmentioning

confidence: 99%

Development of functional agricultural products utilizing the new health claim labeling system in Japan

Maeda‐Yamamoto

Ohtani

2018

Bioscience, Biotechnology, and Biochemistry

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In April 2015, Consumer Affairs Agency of Japan launched a new food labeling system known as "Foods with Function Claims (FFC)." Under this system, the food industry independently evaluates scientific evidence on foods and describes their functional properties. As of May 23, 2017, 1023 FFC containing 8 fresh foods have been launched. Meanwhile, to clarify the health-promoting effects of agricultural products, National Agriculture and Food Research Organization (NARO) implemented the "Research Project on Development of Agricultural Products" and demonstrated the risk reduction of osteoporosis of β-cryptoxanthin rich Satsuma mandarins and the anti-allergic effect of the O-methylated catechin rich tea cultivar Benifuuki. These foods were subsequently released as FFC. Moreover, NARO elucidated the health-promoting effects of various functional agricultural products (β-glucan rich barley, β-conglycinin rich soybean, quercetin rich onion, etc.) and a healthy boxed lunch. This review focuses on new food labeling system or research examining functional aspects of agricultural products.

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“…Some studies describe effects of food supplemented with glucan and psylicia on DM2 occurence (Aoe et al, 2017;McRae, 2018). Beta glucan is established to be an important part of nutrition, which is able to modulate dysregulation of metabolism connected with metabolic syndrome (El Khoury et al, 2012;Lyon and Reichert, 2010;Aoe et al, 2017).…”

Section: Introductionmentioning

confidence: 99%

Diabetic Retinopathy: Changes in Levels of Orosomucoids in Patients Supplemented with Beta Glucan and Vitamin D

Richter¹,

Zahradnicka²,

Ivana³

et al. 2018

American Journal of Immunology

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The role of beta glucan in stimulating of various biological reactions is getting more and more attention. In this report, we focused on the effects of oral supplementation with beta glucan and vitamin D on changes in serum levels of orosomucoids in patients with diabetic retinopathy. We measured the level of orosomucoids and evaluated the effects of oral supplementation. In this study we report significant decrease of orosomucoids levels after the end of the three-month treatment. Our results support the fact that continual supplementation with glucan is necessary for diabetes melitus and diabetic retinopathy patients.

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Effects of high β-glucan barley on visceral fat obesity in Japanese individuals: A randomized, double-blind study

Cited by 88 publications

References 14 publications

Molecular Mechanism of Functional Ingredients in Barley to Combat Human Chronic Diseases

Molecular Mechanism of Functional Ingredients in Barley to Combat Human Chronic Diseases

Development of functional agricultural products utilizing the new health claim labeling system in Japan

Diabetic Retinopathy: Changes in Levels of Orosomucoids in Patients Supplemented with Beta Glucan and Vitamin D

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