Effects of Green Tea Extract and Lactobacillus Casei Strain Shirota on Levels of Serum Minerals, Cholesterol, Triglycerides, Glucose and Lactate in Rats Fed on High-carbohydrate and High-lipid Diets

Abstract

AIM: The objective of the present study was to evaluate the effects of green tea extract and Lactobacillus casei strain Shirota on levels of serum minerals (Ca, Cu, Zn, Fe, Mg and Mn) YÖNTEM: Otuzbeș sağlıklı Wistar albino rat her grupta 5 hayvan olacak șekilde 7 gruba ayrıldı: Kontrol grubu (A), yüksek-karbonhidratlı diyet grubu (B), yüksek karbonhidratlı diyet ve 8 hafta süreyle probiyotik bakteri ilaveli grup-Lactobacillus casei strain Shirota (C), yüksek karbonhidratlı diyet ve 8 hafta süreyle yeșil çay ekstraktı verilen grup (D), yüksek lipit içerikli diyet grubu (E), yüksek lipit içerikli diyet ve 8 hafta süreyle probiyotik bakteri ilaveli grup-Lactobacillus casei strain Shirota (F) ve yüksek lipit içerikli diyet ve 8 hafta süreyle yeșil çay ekstraktı ilaveli grup (G). BULGULAR: Serum kolesterol seviyesinin yüksek lipit ve yüksek lipit + yeșil çay ekstraktı ilaveli gruplarda (grup E ve G) kontrole ve diğer deneme gruplarına göre anlamlı olarak artığı tespit edildi (p<0.05). Serum trigliserid seviyesi yüksek karbonhidrat + probiyotik ilaveli grupta (grup C) diğer

Curcumin as a permeability enhancer enhanced the antihyperlipidemic activity of dietary green tea extract

“…In-vivo study, thus, supported ex-vivo study of increased permeability and then bioavailability of GTE by adding curcumin, leading to more significant serum lipid regulating effect in rats. The results obtained are in close agreement with earlier observations of green tea extract and lactobacillus strain [29]. One of the underlying mechanism by which EGCG affects lipid metabolism is by interfering with the luminal emulsification, hydrolysis, and micellar solubilization of lipids and cholesterol in the digestive tract, which in turn decrease uptake of lipids and cholesterol absorption [34].…”

“…Test group C (Group V) was given high fat diet ad libitum for 15 days and F2 formulation in solution form (0.5 ml), once a day, for further 15 days with a dose of 100 mg/kg/day. At the end of study period, all the animals were anesthetized using isoflurane anaesthesia, blood samples of all groups were collected from retro-orbital sinuses and analysed for serum triglycerides, cholesterol, low density lipoproteins (LDL), High Density Lipoproteins (HDL), and Very Low density lipoproteins (VLDL) [29–31]. After collection of samples, the animals were humanly euthanized/ sacrificed using carbon-dioxide asphyxiation.…”

Hepatoprotective activities of thyme (Thymus vulgaris L.) in rats suffering from obesity.

“…The increase in HDL-ch levels can be a result of the protective mechanism against oxidative stress caused by high fat diet. Also, it may be a mechanism to prevent oxidative alterations in other lipoproteins including LDL-ch [63]. Serum high density lipoprotein cholesterol (HDL-ch): Table (4) exhibits HDL-ch lower concentrations in the rat groups supplemented with thyme powder and essential thyme oil which contain natural antioxidants in comparison with normal control rats.…”