Effects of clopidol on sporulation and infectivity of Eimeria tenella oocysts

Arakawa, Akira; Tanaka, Yuki; Baba, Eiichiroh; Fukata, Tsuneo

doi:10.1016/0304-4017(91)90008-j

Cited by 10 publications

(3 citation statements)

References 9 publications

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“…There is a particular plant in India known as Holorrhena antidysentrica (kurchi) and it is antiprotozoal. Its extract is mixed with that of other plants such as allium spp and berberis making it a good coccidiostat [44][45][46][47]. Alicin, the main constituent of garlic, was extracted and was found to inhibit the sporulation of Eimeria tenella in an in vitro study [48][49][50][51][52].…”

Section: Plant and Extracts Used For Alleviating Coccidiosis In Poultrymentioning

confidence: 99%

Workable Alternatives to Conventional Inputs in Poultry Farming

Ajide,

Opowoye,

Makinde

et al. 2023

Poultry Farming - New Perspectives and Applications

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The world’s demand for poultry products is increasing at an alarming rate, therefore the need for innovations to mitigate the required inputs for sustaining this demand. The challenges of poultry farming attributed to their health, and nutritional requirement is vital to successful poultry production either at a subsistence or at a commercial level. Feed accounts for about 70–80% of the overall production costs. Meeting the nutritional requirements of poultry impacts positively on their health performance. Adequate feeding enables the birds attain table weight earlier than their counterpart that are poorly fed, which could be profitable or not as it depends on the costs of inputs in each production cycle. The essence of poultry farming to an investor is to make profit; however, should poultry farmers continuously make profit, they need to apply workable alternatives suitable for the conventional inputs such as protein, energy sources, plant extracts for orthodox medication, and brooding materials.

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Section: Plant and Extracts Used For Alleviating Coccidiosis In Poultrymentioning

confidence: 99%

Workable Alternatives to Conventional Inputs in Poultry Farming

Ajide,

Opowoye,

Makinde

et al. 2023

Poultry Farming - New Perspectives and Applications

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“…If coccidiosis is manifested in its clinical form, the sulphonamide-based derivatives, i.e. the derivatives of p-aminobenzolsulphonic acid are used for treatment (Arakawa et al 1991;Katzung 1995). Sulphachloropyrazine-4-amino-N(choropyrazinyl)-monosodium monohydrate (active substance of the drug "Esb 3 30%") is a sulphonamide of a wide spectrum of action, (Bevill 1988).…”

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confidence: 99%

Effect of sulphachloropyrazine on antioxidative systems in blood and liver of broilers

et al. 2011

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This report describes the effects of therapeutic doses of coccidiocid sulphachloropyrazine on enzymatic and non-enzymatic antioxidative systems in haemolysed blood and liver homogenate from broilers (glutathione, glutathione-reductase, glutathione-peroxidase, peroxidase, superoxidedismutase, xantine-oxidase and lipid peroxidation). The in vivo investigation was carried out on 120 heavy-line broilers (Arbor acres) of both sexes. One-day-old broilers were randomly distributed into 2 groups, each numbering 60 individuals of both sexes: Group 1 -control group; Group 2 -group of broilers inoculated with laboratory derived coccidia species on the 21 st day-ofage. When symptoms of coccidiosis appeared (30 th day-of-age), blood sampling and decapitation of 20 chickens were carried out (Group 2a). The remaining broilers were treated with therapeutic doses of sulphachloropyrazine (60 ppm). Decapitation of 20 chickens was carried out after the therapy was concluded (38 th day-of-age -Group 2b). Infection of broilers with coccidia intensified free radical processing in haemolysed blood and liver homogenate. This was evident from the increased levels of lipid peroxidation and the catalytic activity of almost all examined enzymes (SOD, GSHPx and Px). Therapeutic doses of sulphachloropyrazine inhibited free-radical activity induced by disease and establishing of physiological values of lipid peroxidation and catalase activity of examined enzymes.

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“…Amprolium, clopidol, monensin, nicarbazin and salinomycin sodium are all commonly used for the treatment of poultry infected with Eimeria spp. (Arakawa et al 1991, Peeters et al 1994, Daugschies et al 1998. Monensin, salinomycin and nicarbazin have been used to completely inhibit the growth of Cryptosporidium parvum (Armson et al 1999), and salinomycin sodium has been demonstrated to reduce the incidence of shedding of Salmonella enteritidis in broilers at 6 wk post-infection (Bolder et al 1999) and to cause irreversible damage to the plasmodial developmental stages of Henneguya sp.…”

Section: Introductionmentioning

confidence: 99%

Efficacy of selected oral chemotherapeutants against Ichthyophthirius multifiliis (Ciliophora: Ophyroglenidae) infecting rainbow trout Oncorhynchus mykiss

Shinn

Wootten²,

Côté³

et al. 2003

Dis. Aquat. Org.

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The chemotherapeutic efficacy of 6 in-feed compounds against Ichthyophthirius multifiliis Fouquet, 1876 was assessed using experimental infections of rainbow trout Oncorhynchus mykiss (Walbaum) fingerlings. Trial doses of 104 ppm amprolium hydrochloride or 65 ppm clopidol fed to fish for 10 d prior to infection significantly reduced the number of trophonts establishing in trout fingerlings by 62.0 and 35.2% respectively. In-feed treatments of infected trout with either 63 or 75 ppm amprolium hydrochloride, 92 ppm clopidol, or 38, 43 or 47 ppm salinomycin sodium for 10 d also significantly reduced the number of surviving trophonts by 77.6 and 32.2% for amprolium, 20.1% for clopidol and 80.2, 71.9 and 93.3% respectively for salinomycin sodium.

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Effects of clopidol on sporulation and infectivity of Eimeria tenella oocysts

Cited by 10 publications

References 9 publications

Workable Alternatives to Conventional Inputs in Poultry Farming

Workable Alternatives to Conventional Inputs in Poultry Farming

Effect of sulphachloropyrazine on antioxidative systems in blood and liver of broilers

Efficacy of selected oral chemotherapeutants against Ichthyophthirius multifiliis (Ciliophora: Ophyroglenidae) infecting rainbow trout Oncorhynchus mykiss

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