Effects of Channa striata Extract on Albumin Serum and Neutrophil-to-Lymphocyte Ratio in Hyperglycemic Rats with Wound Injury: A Randomized Control Study

Taslim, Nurpudji Astuti; Fitriana, Nur; Suprapti, Ni Luh Eka; Marsella, Caroline Prisilia; Bukhari, Agussalim; Rasyid, Haerani; Aminuddin, Aminuddin; As’ad, Suryani; Aman, Andi Makbul; Madjid, Mardiana

doi:10.3889/oamjms.2022.8179

Cited by 5 publications

(3 citation statements)

References 26 publications

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“…Vitamin D receptor also involved in calcium signaling and myogenesis (19,20). Serum vitamin D levels increase after given oral vitamin D(21,22) In this study showed increases serum vitamin D level serum signi cantly after 4 and 8 weeks supplementation compared to the control group. Production of vitamin D can decrease caused by genetic, dark skin color, sunscreen, and limited sunlight exposure, or when cutaneous vitamin D synthesis decrease (19,23,24).…”

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confidence: 49%

Impact of Vitamin D Suplementation in Clinical Outcome at Tuberculosis Spondylitis : Randomized Controlled Trial

Arifin,

Massi,

Biakto

et al. 2024

Preprint

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Mycobacterium tuberculosis (MTB) causes infectious bacterial disease. Most cases of musculoskeletal tuberculosis affect vertebrae which cause spinal tuberculosis (spondylitis), extrapulmonary tuberculosis. Vitamin D deficiency have higher risk in tuberculosis infection. Vitamin D had role in the activation processes on immune cell which eliminate tuberculosis infection. The aim of the study is to assess the impact of oral supplementation of serum vitamin D on clinical outcome in spinal tuberculosis. The study design is randomized controlled trial. Total partisipants is 36 samples. The inclusion criteria were spinal tuberculosis patients diagnosed with MRI and GenExpert. The exclusion criteria were pulmonary tuberculosis, partisipant with other chronic disease such as diabetes, autoimun, malabsorption syndrome. Vitamin D serum levels were measured by ELISA method. There is a significant increasing serum levels of vitamin D in the study group were observed after 4 and 8 supplementation (p< 0.05). On the assessment of ODI and VAS, it decrease significantly in the three groups after 8 weeks of vitamin D supplementation (p<0.05), but in group 10.000 IU also decrease ODI and VAS score significant after 4 weeks supplementation. Trial Registration This study had clinical trial approved by U.S National Library of Medicine (NCT05376189, May 17, 2022).

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confidence: 49%

Impact of Vitamin D Suplementation in Clinical Outcome at Tuberculosis Spondylitis : Randomized Controlled Trial

Arifin,

Massi,

Biakto

et al. 2024

Preprint

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“…In addition, C. striata is used as a postoperative wound medicine, malaria medicine, and typhus (Syafutra et al 2021). The species has anti-inflammatory properties and high albumin levels, so it has been widely used to accelerate postoperative wound healing (Taslim et al 2022). In addition, C. striata has antimicrobial and antinociceptive effects (Sahid et al 2018;Ma'rufi et al 2019).…”

Section: Resultsmentioning

confidence: 99%

Animals ethnozoology as traditional medicine in the Dayak Tamambaloh Tribe, Labian Ira'ang Village, Kapuas Hulu District, Indonesia

et al. 2023

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Abstract. Supiandi MI, Syafruddin D, Gandasari A, Mahanal S, Zubaidah S. 2023. Animals ethnozoology as traditional medicine in the Dayak Tamambaloh Tribe, Labian Ira'ang Village, Kapuas Hulu District, Indonesia. Biodiversitas 24: 26-33. The Dayak Tamambaloh community in Labian Ira'ang Village, Kapuas Hulu District, Indonesia, is a community that has traditional knowledge of the use of fauna. However, at this time this knowledge has been reduced or relegated by the times and the use of animals and has never had a written document. This study aimed to obtain the types of animals used by the Dayak Tamambaloh people for treatment. The method used was a survey. Data was collected through literature studies, semi-structured interviews, and field observations. Data on using animals as traditional medicine was obtained from main informants, key informants, and recommendation informants. Data analysis was descriptive and qualitative, including data collection, data reduction, data presentation, and conclusions. The results obtained 13 types of animals in 13 families that are used as traditional medicine by the Tamambaloh Dayak people. The types of animals used in traditional medicine were wanyi (Apis cerana), asu (Canis lupus familiaris), kandalak (Channa striata), panang (Clarias sp.), bunsok (Gekko gecko), dingkawat (Hipposideros larvatus), lati loman (Lumbricus terrestris), tangkiling (Manis javanica), takiung (Sulcospira testudinaria), manuk (Gallus gallus domesticus), ular sawa (Malayopython reticulatus), lundung (Monopterus albus), and beruang (Ursus thibetanus). Animal families used as traditional medicine were Apidae (1 spesies), Canidae (1 spesies), Channidae (1 spesies), Clariidae (1 spesies), Gekkonidae (1 spesies), Hipposideridae (1 spesies), Lumbricidae (1 spesies), Manidae (1 spesies), Pachychilidae (1 spesies), Phasianidae (1 spesies), Pythonidae (1 spesies), Synbranchidae (1 spesies), and Ursidae (1 spesies). The Dayak Tamambaloh people use meat, bile, scales, shells, egg whites, wax, and all parts of animals for traditional medicine.

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“…The content of compounds in snakehead fish acts as an anti-inflammatory effect that can increase albumin levels and reduce the number of neutrophils in hypoalbuminemia who are injured. Taslim et al (2022) research on hyperglycemic rats with wounds showed that the intervention group on day 10 experienced a decrease in neutrophils and an increase in albumin and lymphocyte values. A decrease in the percentage of neutrophils occurs when there is a decrease in the signal from the proinflammatory sticonyl-17 that suppresses its production in the bone marrow.…”

Section: Effect Of Giving Snakehead Fish Extract (Channa Striata) On ...mentioning

confidence: 99%

An Effect of Giving Snakehead Fish Extract ( Channa striata ) on Albumin, Neutrophil, and Lymphocyte Levels in Hypoalbuminemia Patients

Mustafa

2023

JLT

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Background : Hypoalbuminemia is a condition where the albumin level in the blood falls below normal. Hypoalbuminemia is known as a marker of protein energy malnutrition, inflammation, infection, liver disease, kidney disease and postoperative stress. In Indonesia, malnutrition hospital data shows 40-50% of patients have hypoalbuminemia or are at risk of hypoalbuminemia, 12% of them are severe hypoalbuminemia, and the hospitalization period for patients with hospital malnutrition shows 90% longer than patients with good nutrition. Decreased albumin levels can be associated with a decrease in the immune system and slow healing of tissues/wounds due to infection. Neutrophils and lymphocytes whose numbers increase when inflammation occurs. Oral administration of high protein with snakehead fish extract ( Channa striata ) is an alternative treatment for hypoalbuminemia. Objective: The purpose of this study was to determine the effect of snakehead fish extract (Channa striata) on albumin, neutrophil, and lymphocyte levels in hypoalbuminemic patients. Method: Articles are compiled using a systematic method literature review , involving national and international journals by taking journals through Google scholar, Pubmed, Research Gate, Scient direct. Results: There was an effect of giving snakehead fish extract on albumin levels, neutrophil values, and lymphocyte values in hypoalbuinemic patients and experimental animals. Conclusion: The content of amino acids, albumin, Zn, Fe, Cu and unsaturated fatty acids in snakehead fish ( Ophiocephalus striatus) is quite effective as an effort to increase albumin levels, decrease neutrophil and lymphocyte values when inflammation occurs in hypoalbuminemic patients. Keywords: Channa striata extract , Albumin, Neutrophils, Lymphocytes, Hypoalbuminemia

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Effects of Channa striata Extract on Albumin Serum and Neutrophil-to-Lymphocyte Ratio in Hyperglycemic Rats with Wound Injury: A Randomized Control Study

Cited by 5 publications

References 26 publications

Impact of Vitamin D Suplementation in Clinical Outcome at Tuberculosis Spondylitis : Randomized Controlled Trial

Impact of Vitamin D Suplementation in Clinical Outcome at Tuberculosis Spondylitis : Randomized Controlled Trial

Animals ethnozoology as traditional medicine in the Dayak Tamambaloh Tribe, Labian Ira'ang Village, Kapuas Hulu District, Indonesia

An Effect of Giving Snakehead Fish Extract ( Channa striata ) on Albumin, Neutrophil, and Lymphocyte Levels in Hypoalbuminemia Patients

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