Effects of an anticariogenic casein phosphopeptide on calcium diffusion in streptococcal model dental plaques

Combined CPP-ACP and photoactivated disinfection (PAD) therapy in arresting root surface caries: a case report

“…[2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17] Derived from the milk protein, casein, and digested by the enzyme trypsin, one of the most important features of CPP is their abil ity to stabilise amorphous calcium phos phate (ACP), preventing its precipitation in solution. The spectrum of action of the CPP-ACP complex is broad, buffer ing pH, preventing demineralisation and allowing for remineralisation.…”

Comparison of the newer preventive therapies on remineralisation of enamel in vitro

“…They also demonstrated that CPP-ACP was able to bind to bacterial cells. It was shown that the CPP-ACP bound to Streptococcus mutans and model plaque makes a reservoir of bio-available calcium ions (Rose, 2000, Reynolds et al, 2003.…”

“…The CPP-ACP was shown to promote the remineralisation of enamel subsurface lesions in situ models, This resulted from the localisation of the CPP-ACP in the plaque matrix resulting in a significant increase of the calcium and phosphate ions in supragingival plaque (Reynolds et al, 2003) as well as its bounding to the surface of bacterial cells producing a reservoir of bio-available calcium ions (Rose, 2000, Reynolds et al, 2003. , used the in situ model to assess the remineralisation effect of 2% CPP-ACP dentifrice.…”

Effects of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and fluoride on the microhardness of enamel treated with a bleaching agent: ex vivo

“…Kazein fosfopepit molekülleri fosfoseril içerir ve fosfoseril amorf kalsiyum fosfatı nötral ve alkali koşul-larda stabilize ederek kalsiyum fosfatın çözünürlüğünü artırır. 13 Böylece dişin mineral dolgunluğunun devamını sağlamaktadır. Bununla beraber CPP-ACP'nin aside maruz kalması, ortamda ACP açığa çıkmasına neden olmakta ve ortama salınan kalsiyum ve fosfat iyonları, asidik ortamı da tamponlayarak pH'yi dengelemektedir.…”