“…These included epinhalational anaesthesia, deep intravenous general anaesthesia, topical anaesthesia with lignocaine, drugs like anti hypertensives, beta adrenoreceptor antagonists (propranolol, metoprolol, esmolol, 2 labetolol), Gabapentine, 3 peripheral vasodilators, intravenous lignocainelignocaine aerosol 4,5 Angiotension converting enzyme blockers,Magnesiumsulphate, 6 alpha2 agonist ( Dexmedetomidine, 7 Clonidine 8 ), Droperial, intravenous Ketorolac, Nitroglycerine ointment, Calcium channel blocker, Buprenorphine, Fentanyl [9][10][11][12][13] and Alfentanil. [14][15][16] During laryngoscopy and intubation, fentanyl, µ receptor agonist is a natural choice to attenuate pressor response. 17 Low dose fentanyl decreases the circulatory response to tracheal intubation, reduces the dose of thiopentone, has rapid onset of action, extremely lipid soluble, provides cardiovascular stability throughout the operative period, blocks sympathetic stress response to surgical stimulation, rapid and potent analgesic, anxiolytic and sedative and decreases the concentration of inhaled agent requirement.…”