Effects of Ageing on Small Bowel Video-Capsule Endoscopy Examination

Papadopoulos, Angelos; Triantafyllou, Konstantinos; Kalantzis, C.; Adamopoulos, Adam; Ladas, Dimitris; Kalli, Theodora; Apostolopoulos, Periklis; Kalantzis, Nikolaos; Ladas, Spiros D.

doi:10.1111/j.1572-0241.2008.02090.x

Cited by 32 publications

(20 citation statements)

References 15 publications

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“…Papadopoulos et al investigated 120 consecutive outpatients who underwent VCE for suspected small bowel disease and concluded that: (a) aging did not affect the completion rate and (b) elderly people had more angiodysplasia and tumors than younger patients [11]. On the contrary, Fireman et al, who analyzed 790 subjects retrieved from the Given database, showed that age significantly influenced small bowel transit times [10].…”

Section: Discussionmentioning

confidence: 97%

“…This could be a bias when analyzing VCE findings (secondary end point of the study). Moreover, two different bowel preparations were used in a nonrandomized way in the two centers which participated in the study [11]. In the latter study, a cut-off of 40 years was used to define the elderly group and the completion rate of VCE studies was not considered [10].…”

Section: Discussionmentioning

confidence: 99%

“…Several risk factors for incomplete small bowel VCE examination have been identified [7][8][9]; among these, the influence of aging on VCE procedures is poorly known. Age was either indicated as significantly affecting small bowel transit times during VCE examination in a retrospective study [10] or having no effect in a more recent prospective study [11]. Furthermore, the effect of aging on the performance of VCE in obscure gastrointestinal bleeding (OGIB) has never been prospectively assessed.…”

Section: Introductionmentioning

confidence: 98%

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Age and Video Capsule Endoscopy in Obscure Gastrointestinal Bleeding: A Prospective Study on Hospitalized Patients

et al. 2010

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Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 98%

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Age and Video Capsule Endoscopy in Obscure Gastrointestinal Bleeding: A Prospective Study on Hospitalized Patients

et al. 2010

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“…Various results have been reported for the influence of age on CE, but no consensus has been reached [37,38]. However, it is difficult to prescribe laxatives in large quantity to elderly patients due to the risk of adverse reactions, so to avoid losing the merits of ease of use and noninvasive nature of CE, unnecessary preparations should be avoided.…”

Section: Discussionmentioning

confidence: 99%

Effectiveness of Magnesium Citrate as Preparation for Capsule Endoscopy: A Randomized, Prospective, Open-Label, Inter-Group Trial

Ninomiya

Yao²,

Matsui³

et al. 2012

Digestion

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Background and Aim: Capsule endoscopy (CE) is effective in the detection of small bowel lesions. Many studies have been conducted on the effectiveness of preparations in improving diagnostic yield, but an effective method has yet to be confirmed. We used magnesium citrate as preparation for CE and evaluated its effectiveness. Methods: 50 patients who underwent CE were randomly allocated to two groups – group A (preparation provided) and group B (no preparation). Group A were administered 34 g of magnesium citrate at 8 p.m. the night before the examination. Group B were not administered a laxative. Results: The cleansing efficacy score was 24.4 ± 4.4 points for group A and 22.9 ± 4.4 points for group B, with no significant difference between groups. No significant difference was seen in the large bowel arrival rate between groups: 14 cases (63.6%) for group A and 16 cases (72.7%) for group B. Conclusion: In this study, superiority was not seen for cleansing efficacy, large bowel arrival rate for the preparation method involving administration of hypertonic MC solution 12 h prior to the procedure.

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“…However, recent studies have suggested that this was true only in western populations and that ulceration was the most common etiology in Asian populations [9, 11, 12]. In this study, 532 patients with OGIB in our hospital from 2006 to 2012 were examined by CE or DBE and the etiologies were retrospectively analyzed.…”

Section: Introductionmentioning

confidence: 99%

Small Bowel Endoscopy Diagnostic Yield and Reasons of Obscure GI Bleeding in Chinese Patients

Hao

Yang

et al. 2014

Gastroenterology Research and Practice

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Aim. To investigate the diagnostic yield and etiologies of patients with obscure gastrointestinal bleeding (OGIB) using capsule endoscopy (CE) or double-balloon enteroscopy (DBE). Method. We studied the data of 532 consecutive patients with OGIB that were referred to Xinqiao Hospital in Chongqing from December 2005 to January 2012. A lesion that was believed to be the source of the bleeding (ulceration, mass lesion, vascular lesion, visible blood, inflammation, or others) was considered to be a positive finding. We analyzed the diagnostic yield of CE and SBE and the etiologies of OGIB. Result. CE and SBE have similar diagnostic yields, at 71.9% (196/231) and 71.8% (251/304), respectively. The most common etiology was erosions/ulceration (27.1%) followed by mass lesion (19.4%) and angiodysplastic/vascular lesions (13.9%). By stratified analysis, we found that erosions/ulceration (27.1%) was the most common etiology for the 21–40-year age group. Mass lesion was the most common etiology in the 41–60-year age group. However, in the >60 years age group, angiodysplastic/vascular lesions were significantly increased compared with the other groups, even though erosions/ulceration was most common. Conclusion. In this study, we found that CE and SBE have similar diagnostic yields and erosions/ulceration was the most common reason for OGIB, followed by mass lesion and angiodysplasias.

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Effects of Ageing on Small Bowel Video-Capsule Endoscopy Examination

Abstract: Ageing does not affect the completion rate and the quality of bowel preparation for VCE. However, elderly patients have fewer normal studies and more angiodysplasias and tumors in the small bowel.

Cited by 32 publications

References 15 publications

Age and Video Capsule Endoscopy in Obscure Gastrointestinal Bleeding: A Prospective Study on Hospitalized Patients

Age and Video Capsule Endoscopy in Obscure Gastrointestinal Bleeding: A Prospective Study on Hospitalized Patients

Effectiveness of Magnesium Citrate as Preparation for Capsule Endoscopy: A Randomized, Prospective, Open-Label, Inter-Group Trial

Small Bowel Endoscopy Diagnostic Yield and Reasons of Obscure GI Bleeding in Chinese Patients

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