SUMMARY
BackgroundOctreotide has shown to be effective against rebleeding from gastrointestinal angiodysplasias, but a long-term daily parenteral administration is recommended. Long-acting octreotide (LAR-OCT) could overcome such a limitation, but it has not been studied extensively.
Among patients with undetectable Tg, negative US, and positive TgAb after ablation with (131)I, the frequency of structural disease was <5% in patients, with >50% reduction in TgAb. Among patients without a significant reduction in TgAb, approximately 10% of low-risk patients and >20% of intermediate-risk patients had structural disease. These results help define the indication for imaging methods other than US during initial assessment and long-term follow-up.
An important decline in serum Tg occurred between 3 and 6 months after total thyroidectomy. One year after surgery, Tg was undetectable in approximately 60% of the patients and was ≤2 ng/mL in all of them.
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